A comparative study of Epidural Nalbuphine vs Tramadol as an adjuvant to 0.2% Ropivaciane for post operative pain relief in unilateral total knee replacement surgeries.

This study is a randomized control double blind study , single centre trial comparing the efficacy of Nalbuphine 0.2mg/ml and Tramadol 2mg/ml as an adjuvant to 0.2% Ropivacaine epidurally for post-op analgesia in unilateral total knee replacement surgery. Total sample size is 50 patients divided in two equal groups. The primary outcome measures will be difference in VAS score between groups at 30 minutes, 60 minutes, 2 hours, 4 hours, 6 hours, 12 hours and 24 hours. The secondary outcomes will be patient satisfaction, post-op nausea and vomiting and requirement of breakthrough analgesia.