Influence of Nutritional Status on Rehabilitation Outcome in Subacute Stroke Patients

change in hand grip strenght test score

时间窗: Baseline (T0), Treatment (6 weeks) (T1)

it is a test to measure the maximum isometric strenght of the hand and forearm muscles

change in Body Mass Index

时间窗: Baseline (T0), Treatment (6 weeks) (T1)

it is a measure of body fat based on height and weight that applies to adult men and women expressed in kg/m²

change in food income detection

时间窗: Baseline (T0), Treatment (6 weeks) (T1)

detection of food intake by measurement of portion of dish assumed from the patients

change in Time Up & Go test (TUG) scores

时间窗: Baseline (T0), Treatment (6 weeks) (T1)

The Time Up And Go is a test used to assess mobility, balance, and walking in people with balance impairments. The subject must stand up from a chair (which should not be leant against a wall), walk a distance of 3 meters, turn around, walk back to the chair and sit down - all performed as quickly and as safely as possible. Time will be measured using a chronometer.

change in Neuropathic Pain Four Questions (DN4) scores

时间窗: Baseline (T0), Treatment (6 weeks) (T1)

The DN4 used to evaluate presence of neuropathic pain, and consist of a brief interview of four questions answered yes/no: two on what the patient has conceived and two during the exam for the evaluation of hypoesthesia to the touch or sting and the evaluation of allodynia with the skimming of the skin. For each 'yes' a point is assigned. The total score is given by the sum of the individuals. The cut off for the presence of neuropathic pain is '4'.

change in Mini nutritional Assessment (MNA) scores

时间窗: Baseline (T0), Treatment (6 weeks) (T1)

it is a questionnaire that evaluates the nutritional status

change in Barthel index (BI) scores

时间窗: Baseline (T0), Treatment (6 weeks) (T1)

The BI is designed to assess the ability of an individual with a neuromuscular or musculoskeletal disorder to care for him/herself. It ranges from 0 to 100, with a higher number meaning better performance in activities of daily living.

change in Modified Ashworth Scale (MAS) scores

时间窗: Baseline (T0), Treatment (6 weeks) (T1)

The MAS is a 6 point ordinal scale used for grading hypertonia in individuals with neurological diagnoses. A score of 0 on the scale indicates no increase in tone while a score of 4 indicates rigidity. Tone is scored by passively moving the individual's limb and assessing the amount of resistance to movement felt by the examiner.

change in glucose serum levels

时间窗: Baseline (T0), Treatment (6 weeks) (T1)

serum measurements of glucose in mg/dL

change in magnesium serum levels

时间窗: Baseline (T0), Treatment (6 weeks) (T1)

serum measurements of magnesium in mg/dL

change in creatinin serum levels

时间窗: Baseline (T0), Treatment (6 weeks) (T1)

serum measurements of creatinin in mg/dL

change in iron serum levels

时间窗: Baseline (T0), Treatment (6 weeks) (T1)

serum measurements of iron in microg/dL

change in Motricity Index (MI) scores

时间窗: Baseline (T0), Treatment (6 weeks) (T1)

The MI aims to evaluate lower limb motor impairment after stroke, administrated on both sides. Items to assess the lower limbs are 3, scoring from 0 to 33 each: (1) ankle dorsiflexion with foot in a plantar flexed position (2) knee extension with the foot unsupported and the knee at 90° (3) hip flexion with the hip at 90° moving the knee as close as possible to the chin. (no movement: 0, palpable flicker but no movement: 9, movement but not against gravity :14, movement against gravity movement against gravity: 19, movement against resistance: 25, normal:33).

change in Six-Minute Walking Test (6MWT) scores

时间窗: Baseline (T0), Treatment (6 weeks) (T1)

The 6MWT measures the distance a subject covers during an indoor gait on a flat, hard surface in 6 minutes, using assistive devices, as necessary. The test is a reliable and valid evaluation of functional exercise capacity and is used as a sub-maximal test of aerobic capacity and endurance. The minimal detectable change in distance for people with sub-acute stroke is 60.98 meters. The 6MWT is a patient self-paced walk test and assesses the level of functional capacity. Patients are allowed to stop and rest during the test. However, the timer does not stop. If the patient is unable to complete the test, the time is stopped at that moment. The missing time and the reason of the stop are recorded. This test will be administered while wearing a pulse oximeter to monitor heart rate and oxygen saturation, also integrated with Borg scale to assess dyspnea.

change in blood levels of systemic oxidative stress (dROMs)

时间窗: Baseline (T0), Treatment (6 weeks) (T1)

dROMs test measures circulating hydroperoxides (UCarr)

change in antioxydant capacity of serum (BAP)

时间窗: Baseline (T0), Treatment (6 weeks) (T1)

BAP test measures total antioxidant status in serum in micromol/L

change haemoglobin serum levels

时间窗: Baseline (T0), Treatment (6 weeks) (T1)

serum measurements of haemoglobin g/dL

change in albumine serum levels

时间窗: Baseline (T0), Treatment (6 weeks) (T1)

serum measurements of glucose in g/dL

weight change

时间窗: Baseline (T0), Treatment (6 weeks) (T1)

detection of the weight drop or weight increase

change in Bioimpedance analysis (BIA) measurements

时间窗: Baseline (T0), Treatment (6 weeks) (T1)

it is a non-invasive measurement of body fat, lean muscle mass and hydration

change in Fugl-Meyer Assessment of Motor Recovery after Stroke for Upper Extremity portion (FMA-UL) scores

时间窗: Baseline (T0), Treatment (6 weeks) (T1)

The FMA-UL is a stroke-specific, performance-based impairment index. It is designed to assess motor functioning, sensation and joint functioning in patients with post-stroke hemiplegia. The upper limb portion of the FMA-UL ranges from 0 (hemiplegia) to 66 points (normal upper limb motor performance)

change in Numerical Rating Scale (NRS) scores

时间窗: Baseline (T0), Treatment (6 weeks) (T1)

The Numeric Rating Scale (NRS) is the simplest and most commonly used numeric scale to rate the pain from 0 (no pain) to 10 (worst pain).

change in thiol serum levels (SHp)

时间窗: Baseline (T0), Treatment (6 weeks) (T1)

SHp test measures the circulating thiolic antioxidants in serum in micromol/L

change in triglycerides serum levels

时间窗: Baseline (T0), Treatment (6 weeks) (T1)

serum measurements of triglycerides in mg/dL

change in total cholesterol serum levels

时间窗: Baseline (T0), Treatment (6 weeks) (T1)

serum measurements of total cholesterol in mg/dL

change in latent iron binding capacity serum levels

时间窗: Baseline (T0), Treatment (6 weeks) (T1)

serum measurements of latent iron binding capacity in microg/dL

change in 10 Meter Walk Test scores

时间窗: Baseline (T0), Treatment (6 weeks) (T1)

This test will assess the patient's speed during gait. Patients will be asked to walk at their preferred maximum and safe speed. Patients will be positioned 1 meter before the start line and instructed to walk 10 meters, and pass the end line approximately 1 meter after. The distance before and after the course are meant to minimize the effect of acceleration and deceleration. Time will be measured using a stopwatch and recorded to the one hundred of a second (ex: 2.15 s). The test will be recorded 3 times, with adequate rests between them. The average of the 3 times should be recorded.

change in HDL cholesterol serum levels

时间窗: Baseline (T0), Treatment (6 weeks) (T1)

serum measurements of HDL cholesterol in mg/dL

change in calcium serum levels

时间窗: Baseline (T0), Treatment (6 weeks) (T1)

serum measurements of calcium in mg/dL

change in hepatic status serum levels (ALT-GPT)

时间窗: Baseline (T0), Treatment (6 weeks) (T1)

serum measurements o ALT-GPT in U/L