NCT01306539已完成不适用
Neuropsychiatric Effects of Deep Brain Stimulation in Patients With Parkinson's Disease
适应症
干预措施
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 20
- 试验地点
- 2
- 主要终点
- behavioral task performance
研究概览
简要总结
Stimulation of the subthalamic nucleus will have effects on various aspects of neuropsychiatric function.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Basic Science
- 盲法
- Double
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Participants diagnosed with idiopathic Parkinson's disease that meet criteria for treatment of their disease with STN-DBS. Participants will be selected for this study without regard for age (provided they are older than 18), gender or ethnic background.
- •Participants must have undergone subthalamic nucleus DBS surgery and be receiving treatment at the Scripps Clinic in La Jolla, CA
排除标准
- •Patients under 18 years old.
- •Patients with mini-mental status scores below 26/
- •Patients with known psychiatric disease.
- •Patients who are too infirm, demented or dysarthric to clearly understand the consenting process, task instructions, or to communicate verbally regarding participation or non-participation.
研究组 & 干预措施
Deep Brain Stimulation
Experimental
Parkinson's patients with deep brain stimulation in the subthalamic nucleus.
干预措施: Stimulation of the subthalamic nucleus (Procedure)
结局指标
主要结局
behavioral task performance
时间窗: 1 to 2 hours
Participants will complete behavioral tasks at each of three visits to assess the effects of stimulation settings on task performance. At each research visit, behavior will be assessed beginning at 1 hour after the stimulation is adjusted to the experimental settings. Stimulation settings will be returned to each patient's treatment levels at the culmination of each visit.
次要结局
未报告次要终点
研究者
Adam Aron
Professor
University of California, San Diego
研究点 (2)
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