Follow Up Study for Treatment of Parkinson's Disease With Subthalamic Deep Brain Stimulation
Completed
- Conditions
- Parkinson Disease
- Registration Number
- NCT03230331
- Lead Sponsor
- Ruijin Hospital
- Brief Summary
This study aims to evaluate the long term effect of deep brain stimulation in the the subthalamic nucleus (STN) in patients with Parkinson's disease.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 20
Inclusion Criteria
- Idiopathic Parkinson's disease
- Disease duration longer than 15 years
- Had STN deep brain stimulation implant more than 10 years
- Available and willing to be followed-up according to study protocol
Exclusion Criteria
- Patients with serious diseases such as tumor, sever liver or kidney dysfunction were not selected in the clinical trials
- Epilepsy
- Pregnant female
- History of severe neuropsychiatric disease
- Patients are taking part in other clinical trials in recent several months
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Changs in the score of Stand-Walk-Sit Test above 10 years post surgery
- Secondary Outcome Measures
Name Time Method UPDRS part II score above 10 years post surgery Freezing of Gait Questionnaire (FOG-Q) score above 10 years post surgery Apathy Evaluation Scale score above 10 years post surgery Change of the score in United Parkinson Disease Rating Scale (UPDRS) part III above 10 years post surgery 39-Item Parkinson´s Disease Questionnaire (PDQ-39) score above 10 years post surgery Gait and Falls Questionnaire (GFQ) score above 10 years post surgery Mini-Mental State Examination (MMSE) score above 10 years post surgery Frontal Assessment Battery (FAB) score above 10 years post surgery Hamilton Depression Scale-17 (HAMD-17) score above 10 years post surgery UPDRS part I score above 10 years post surgery UPDRS part IV score above 10 years post surgery Montreal Cognitive Assessment (MoCA) Beijing score Version above 10 years post surgery Hamilton Anxiety Scale (HAMA) score above 10 years post surgery
Trial Locations
- Locations (1)
Ruijin Hospital affiliated to Shanghai Jiao Tong University School of Medicine
🇨🇳Shanghai, China