NCT00952796已完成4 期
A Comparative Study of Ampicillin/Sulbactam Versus Moxifloxacin in the Treatment of Complicated Intra-abdominal Infections
适应症
干预措施
相关药物
试验速览
- 阶段
- 4 期
- 状态
- 已完成
- 入组人数
- 100
- 试验地点
- 1
- 主要终点
- clinical response at test-of-cure visit
研究概览
简要总结
On the basis of monotherapy for intra-abdominal infection, the investigators are conducting this study to identify the difference of drug efficacy between ampicillin/sulbactam and moxifloxacin.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Single (Participant)
入排标准
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •patients diagnosed of complicated intra-abdominal infection need surgical treatment
排除标准
- •patients diagnosed of intra-abdominal infection receive non-operative management
- •patients with known allergic history of fluoroquinolone
- •Severe, life threatening disease with a life expectancy of < 48 h or APS and APACHE scores of > 35
研究组 & 干预措施
1
Experimental
patients with intra-abdominal infection treated with moxifloxacin 400mg once daily
干预措施: moxifloxacin (Drug)
2
Active Comparator
patients with intra-abdominal infection treated with ampicillin/sulbactam 1.5g 4 times daily
干预措施: ampicillin/sulbactam (Drug)
结局指标
主要结局
clinical response at test-of-cure visit
时间窗: test of cure: 10-14 days after initial treatment
次要结局
未报告次要终点
研究者
研究点 (1)
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