NCT07646197招募中不适用
Impacts of Peanut Intake on Hepatic Markers and Gut Microbiota in Adults With MASLD
适应症
干预措施
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 125
- 试验地点
- 1
研究概览
简要总结
The aim of this randomized interventional trial is to understand the effects of peanut consumption on patients with metabolic associated fatty liver. The main goal is to investigate if patients who consume peanuts have improved liver marker tests as well as metabolic profile. We will also investigate how peanuts alter the gut microbes and liver fat content in patients with metabolic associated fatty liver.
- Participants will be randomized into intervention (peanut consumption for 12 weeks) and control (regular diet) arm.
- Stool sample and blood (for biomarkers) collection across both arms at baseline and post-intervention
- Daily log to be completed for tracking peanut consumption
- 2-day Dietary recall at baseline, during Week 6 and Week 12
- Poat intervention Fibro scans for participants with baseline scans available
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Supportive Care
- 盲法
- None
入排标准
- 年龄范围
- 30 Years 至 70 Years(Adult, Older Adult)
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •30-70 years
- •do not consume peanut/peanut butter/treenut/seeds > /week
- •at least one encounter-related (stage F0/F1) MASLD diagnosis (K76.0)
- •Able to understand, speak, and read English
- •Mentally competent to consent
排除标准
- •Food allergy to peanuts or peanut-containing products
- •With alcohol use disorder (AUDIT screening)
- •Other types of cancer
- •Heart or cardiovascular diseases (such as heart attack, stroke, heart failure)
- •Kidney diseases (such as chronic kidney disease, kidney transplant, renal insufficiency such as renal failure requiring dialysis)
研究组 & 干预措施
Peanut
Experimental
MASLD patients will consume 50 gm of peanut daily for 12 weeks
干预措施: Peanut consumption (Other)
Control
No Intervention
Regular diet
研究者
Menghua Tao
Assistant Scientist
Henry Ford Health System
研究点 (1)
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