Impact of Non-invasive Brain Stimulation on Motor Recuperation
试验速览
- 阶段
- 不适用
- 状态
- 暂停
- 发起方
- 入组人数
- 200
- 试验地点
- 1
- 主要终点
- change in motor function before/after tDCS
研究概览
简要总结
tDCS (transcranial direct current stimulation) will be used in chronic stroke patients to improve a variety of functions with superior or inferior limb.
详细描述
tDCS will be used in chronic stroke patients to improve a variety of functions such as motor functions with superior or inferior limb.
tDCS will be applied in a placebo-controlled, double-blind, randomised fashion. Behavioural data will be collected before and after tDCS, as well as brain functional imaging data.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Crossover
- 主要目的
- Treatment
- 盲法
- Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)
盲法说明
no change
入排标准
- 年龄范围
- 18 Years 至 90 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •stroke with at least slight deficit in superior or inferior limb
排除标准
- •contraindication to tDCS and/or to fMRI
- •presence of metal in the head
- •inability to understand/complete behavioural tasks
- •chronic intake of alcohol or recreative drugs
- •major health condition
- •presence of pacemaker
- •pregnancy
结局指标
主要结局
change in motor function before/after tDCS
时间窗: Baseline (>6 months after stroke), immediately after intervention (30min of tDCS), 10-20-30-40-50-60 min after intervention; long-term after intervention : 1-2-3-4 weeks
Motor performance improvement with inferior or superior limb
次要结局
未报告次要终点
研究者
Pr Yves Vandermeeren, MD, PhD
Professor
University Hospital of Mont-Godinne