Evaluation of induction characteristics of Propofol and Etomidate for I-gel insertion using Bispectral Index (BIS) guided induction of General Anaesthesia. A prospective randomised double-blinded clinical trial.
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 发起方
- 入组人数
- 60
- 试验地点
- 1
- 主要终点
- Time taken to achieve BIS50
研究概览
简要总结
•After taking informed consent ,patients will be randomly assigned to one of the 2 group according to computer generated random number table.
Group P – this group of participants will receive Infusion Propofol till BIS 50 is achieved
Group E – this group of participants will receive Infusion Etomidate till BIS 50 is achieved.
•The total time taken to reach BIS 50 will be calculated.
•Dose required to achieve BIS 50 will be noted.
•Ease of I-gel insertion by degree of jaw relaxation and overall I-gel insertion conditions will be assessed.
•Haemodynamic changes and other adverse effects will be noted.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 盲法
- Participant and Investigator Blinded
入排标准
- 年龄范围
- 18.00 Year(s) 至 60.00 Year(s)（—）
- 性别
- All
入选标准
- •ASA 1 and 2 2)BMI less than 35 3)Posted for elective surgery under general anaesthesia.
排除标准
- •Posted for emergency surgery 2)Allergic to propofol and etomidate 3)Anticipated difficult airway 4)Adrenal insufficiency or seizure patients 5)Pregnant females.
结局指标
主要结局
Time taken to achieve BIS50
时间窗: Time taken to achieve BIS50 at baseline ,before start of induction agent infusion,before i gel insertion,1 minute after i gel insertion,3 minutes after i gel insertion,5 minutes after i gel insertion
次要结局
- Dose required to achieve BIS 50(Igel ease of insertion characterstics)
研究者
Sai Mani Kanta Bandla
All India Institute Of Medical Sciences, Rajkot