Effect of the High Impact Exercise on Bone Density in Prepuberal Girls in 12 Private Schools in Bogota - Colombia During 2016 - 2017. Open Label Randomized Controlled Trial
试验速览
- 阶段
- 不适用
- 状态
- 暂停
- 发起方
- 入组人数
- 276
- 主要终点
- bone mineral density (BMD) are presented for the total Body total bone mineral density
研究概览
简要总结
Osteoporosis has become a worldwide concern an a matter of public health as osteoporosis is a major contributing factor associated with insufficiency fracture of the spine, wrist and proximal femur, and as a result, can diminish quality of life as well as increase direct and indirect healthcare costs.
The pathophysiology of osteoporosis is based on two main factors; low bone mass and age associated architectural changes within the bone, high impact exercise in childhood can improve the peak bone mass and bone architecture. The evidence suggests that bone adaptation to increased load is optimal in early puberty (Tanner stages I and II) since around 30% of total body adult bone mass is accrued during this period.
However, the optimal exercise program for increasing peak bone mineral content is still unclear. Therefore, the aim of this study is to assess if 15 minutes of high-impact exercise three times per week improve areal bone mineral density assessed by DXA of pre pubertal girls after a ten-month regimen compared to low-impact exercise. This information could highly impact the development of public health policies directed to pre pubertal girls.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 盲法
- Single (Outcomes Assessor)
入排标准
- 年龄范围
- 8 Years 至 10 Years(Child)
- 性别
- Female
- 接受健康志愿者
- 是
入选标准
- •Girls between ages 8 to 10
排除标准
- •Precocious menarche (within the selected timeframe)
- •Chronic disorders or medications known to affect bone metabolism or musculoskeletal function.
- •Body Mass Index 30 or higher
- •Regular vigorous physical activity (training more than 8 hours per week)
结局指标
主要结局
bone mineral density (BMD) are presented for the total Body total bone mineral density
时间窗: 36 weeks
whole body whole Amount of mineral matter per square centimeter of bones.
次要结局
未报告次要终点
研究者
ANA KARINA SARMIENTO
ORAL AND MAXILLOFACIAL SURGEON
Fundación Santa Fe de Bogota
