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临床试验/NCT06840639
NCT06840639已完成不适用

The Impact of Dental Health on Complications During and Following Radiotherapy in the Head and Neck Region.

Lund University Hospital1 个研究点 分布在 1 个国家目标入组 750 人开始时间: 2024年1月1日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
750
试验地点
1
主要终点
Does dental extractions increase the risk for complications such as osteoradionecrosis?

研究概览

简要总结

Study the risk of complications after dental extractions in patients recieving radiotherapy.

详细描述

Dental extractions before radiotherapy in the head and neck region is an established part of the treatment plan for patients with malignant disease. There are contradictory results in the literature regarding the importance timing and magnitude of extractions. It is important to minimize complications in this patient group since the regular therapy is already detrimental to the affected tissues. Patients were extracted from the ARTSCAN register were the population was followed for 4 years for several factors, including development of osteoradionecrosis. The aim is to evaluate which diagnoses are more prone to develop complications after extraction. If there is a relationship between occurrence of complication and magnitude of dental pathology.

研究设计

研究类型
Observational
观察模型
Case Control
时间视角
Other

入排标准

年龄范围
18 Years 至 —(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • Malignant diagnosis
  • radiotherapy pre or postoperative

排除标准

  • 未提供

结局指标

主要结局

Does dental extractions increase the risk for complications such as osteoradionecrosis?

时间窗: From diagnosis of head and neck pathology, approximately 1 month before start of radiotherapy, and to the end of the medical record which may be from one year after the oncologic treatment up to 26 years after oncologic treatment.

Type of complication when extracting teeth in conjunction with radiotherapy.

Does dental pathology in extracted teeth correlate with development of osteoradionecrosis?

时间窗: From diagnosis of head and neck pathology, approximately 1 month before start of radiotherapy, and to the end of the medical record which may be from one year after the oncologic treatment up to 26 years after oncologic treatment.

Are any specific dental pathology more prone to develop complications than others?

次要结局

未报告次要终点

研究者

申办方类型
Other
责任方
Sponsor

研究点 (1)

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