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临床试验/EUCTR2012-004704-35-NL
EUCTR2012-004704-35-NL进行中(未招募)不适用

Thiazide diuretics versus calcium channel blockers for the treatment of tacrolimus-induced hypertension in dermatology patients: a single-center randomized cross-over trial. - TT-study

未提供0 个研究点开始时间: 2012年11月16日最近更新:
适应症

试验速览

阶段
不适用
状态
进行中(未招募)

研究概览

简要总结

暂无简介。

研究设计

研究类型
Interventional clinical trial of medicinal product

入排标准

性别
All

入选标准

  • Treatment with tacrolimus
  • MDRD-GFR = 30 ml/min
  • Systolic blood pressure > 140 mmHg but < 180 mmHg during 24-hours blood pressure measurement
  • Stable background antihypertensive drugs (i.e., no anticipated change in dose during the study period)
  • 18 years or older
  • Are the trial subjects under 18? no
  • Number of subjects for this age range:
  • F.1.2 Adults (18-64 years) yes
  • F.1.2.1 Number of subjects for this age range 10
  • F.1.3 Elderly (>=65 years) no
  • F.1.3.1 Number of subjects for this age range 5

排除标准

  • MDRD-GFR < 30 ml/min
  • Serum sodium < 136 mmol/l
  • Serum potassium < 3.5 mmol/l
  • Proteinuria > 1.0 g/10 mmol creatinine
  • Systolic blood pressure < 140 mmHg during 24-hour blood pressure measurement
  • Systolic blood pressure > 180 mmHg during 24-hour blood pressure measurement
  • The use of co-trimoxazol or prednisone
  • Incapacitated subjects
  • Pregnancy
  • Use of a thiazide diuretic in combination with a calcium channel blocker
  • Use of loop diuretics

研究者

发起方
未提供

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