EUCTR2012-004704-35-NL进行中(未招募)不适用
Thiazide diuretics versus calcium channel blockers for the treatment of tacrolimus-induced hypertension in dermatology patients: a single-center randomized cross-over trial. - TT-study
未提供0 个研究点开始时间: 2012年11月16日最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 进行中(未招募)
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional clinical trial of medicinal product
入排标准
- 性别
- All
入选标准
- •Treatment with tacrolimus
- •MDRD-GFR = 30 ml/min
- •Systolic blood pressure > 140 mmHg but < 180 mmHg during 24-hours blood pressure measurement
- •Stable background antihypertensive drugs (i.e., no anticipated change in dose during the study period)
- •18 years or older
- •Are the trial subjects under 18? no
- •Number of subjects for this age range:
- •F.1.2 Adults (18-64 years) yes
- •F.1.2.1 Number of subjects for this age range 10
- •F.1.3 Elderly (>=65 years) no
- •F.1.3.1 Number of subjects for this age range 5
排除标准
- •MDRD-GFR < 30 ml/min
- •Serum sodium < 136 mmol/l
- •Serum potassium < 3.5 mmol/l
- •Proteinuria > 1.0 g/10 mmol creatinine
- •Systolic blood pressure < 140 mmHg during 24-hour blood pressure measurement
- •Systolic blood pressure > 180 mmHg during 24-hour blood pressure measurement
- •The use of co-trimoxazol or prednisone
- •Incapacitated subjects
- •Pregnancy
- •Use of a thiazide diuretic in combination with a calcium channel blocker
- •Use of loop diuretics
研究者
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