EFFECT OF A SINGLE INTRAOPERATIVE DOSE OF DEXAMETHASONE ON GLYCEMIC PROFILE IN POST OPERATIVE PATIENTS, UNDERGOING ELECTIVE LAPAROSCOPIC SURGERY UNDER GENERAL ANAESTHESIA: RANDOMISED CONTROLLED TRIAL
试验速览
- 阶段
- Phase 3 4
- 状态
- 尚未招募
- 发起方
- 入组人数
- 100
- 试验地点
- 1
- 主要终点
- To compare the changes in the glycemic profile up to 72hours in patients receiving a single dose of dexamethasone in elective laparoscopic surgery
研究概览
简要总结
This study will be conducted in the department of Anaesthesiology, Dr. S. N. MEDICAL COLLEGE and associated group of hospitals on patients posted for laparoscopic surgery . The aim is to study the effect of a single dose of dexamethasone on glycemic profile up to 72hours in postoperative patients undergoing elective laparoscopic surgery under general anaesthesia and also to compare the incidence of postoperative nausea and vomiting (PONV) and Postoperative pain in term of VAS score.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 盲法
- Participant and Investigator Blinded
入排标准
- 年龄范围
- 18.00 Year(s) 至 70.00 Year(s)（—）
- 性别
- All
入选标准
- •The patients of aged 18-70 years with Body Mass Index (BMI) ranging from 18.5 to 24.9 kg/m2, American Society of Anesthesiologists (ASA) physical status I and non-diabetic ASA II status posted for elective laparoscopic surgery will be recruited and studied for 72 hours.
排除标准
- •Candidates with preexisting diabetes mellitus (FBS more than 126 mg/dl, postprandial blood sugar (PPBS) more than 200 mg/dl, HbA1c more than 6.5), Chronic steroid therapy (taking steroid more than 10mg, for more than 10 days within last 10 months), History of allergy to dexamethasone, Pregnancy, History of peptic ulcer disease, Malignancy, Duration of anaesthesia more than 2 hours, Patients who have history of any vomiting, Retching, or nausea in the 24 hours preceding the administration of anaesthesia.
结局指标
主要结局
To compare the changes in the glycemic profile up to 72hours in patients receiving a single dose of dexamethasone in elective laparoscopic surgery
时间窗: To compare the changes in the glycemic profile up to 72hours in patients receiving a single dose of dexamethasone in elective laparoscopic surgery
次要结局
- To compare the incidence of postoperative nausea and vomiting (PONV)(And Postoperative pain in term of VAS score.)
研究者
jyoti
Dr SN Medical College, Jodhpur , Rajasthan