NCT00609453已完成不适用
Brain Imaging of Psychotherapy for Depression (Includes, "Reward System Recovery Following Behavioral Activation Therapy in Depression")
适应症
干预措施
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 27
- 试验地点
- 1
- 主要终点
- Functional Magnetic Resonance Imaging
研究概览
简要总结
The goal of the proposed research is to examine the neural correlates of depressive symptom reduction in individuals with major depressive disorder using functional magnetic resonance imaging (fMRI), and to compare results to those obtained from a nondepressed control group.
研究设计
- 研究类型
- Interventional
- 分配方式
- Non Randomized
- 干预模型
- Single Group
- 盲法
- None
入排标准
- 年龄范围
- 21 Years 至 55 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •For group 1: Diagnosis of current depression and no other current Axis I psychiatric disorder
- •For group 1: Hamilton Depression Rating Scale score of 15 or greater
排除标准
- •A history of serious head injury or neurological disease or psychosis
- •Current use of psychoactive medications
- •Factors that could affect MRI safety including current or planned pregnancy
- •For group 2: current Axis I psychiatric disorder, as assessed by structured clinical interview
研究组 & 干预措施
1
Experimental
Individuals with major depressive disorder receiving therapy
干预措施: Brief Behavioral Activation Treatment for Depression (Behavioral)
结局指标
主要结局
Functional Magnetic Resonance Imaging
时间窗: twice in 12 weeks
Hamilton Depression Inventory
时间窗: three times over 12 weeks
次要结局
未报告次要终点
研究者
Gabriel Dichter
Associate Professor of Psychiatry
University of North Carolina, Chapel Hill
研究点 (1)
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