High Intensity Interval Training for thE Rehabilitation of Geriatric Patients - a Feasibility Pilot studY.
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 100
- 试验地点
- 1
- 主要终点
- Proportion of patients who complete the rehabilitation program
研究概览
简要总结
This is a pilot study for evaluating the feasibility of using High Intensity Interval Training in geriatric hospitalized patients compared to the standard current rehabilitation practice.
详细描述
High Intensity Interval Training (HIIT) has shown a superior effectiveness and efficiency when compared to Moderate Intensity Continuous Training (MICT) in several types of patients and in healthy subjects. There are no data on HIIT in a general geriatric population. This study is a pilot study evaluating the feasibility of using HIIT in geriatric hospitalized patients compared to the standard current rehabilitation practice without HIIT. It is our desire to perform a larger randomized comparative trial between HIIT and MICT if the pilot study proves its feasibility.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 盲法
- None
入排标准
- 年龄范围
- 65 Years 至 —（Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients aged 65 years and older hospitalized for rehabilitation after an acute medical condition
- •Expected duration of the rehabilitation ≥ 2 weeks
- •Ability to follow instructions to perform a Timed up and Go Test
- •Ability to perform exercises
- •Willing to participate in 4 sessions of HIIT per week for 2 weeks
排除标准
- •Any acute condition with tachycardia, hypotension or fever.
- •Abnormal cycle ergometer stress test with
- •significant ECG modification
- •decrease of more than 20 mmHg of the blood pressure with exercise
- •ST depression at a workload <6 METs
- •Inability to reach an intensity of 15/20 in the Borg's scale of perceived exertion
- •Any unresolved acute medical or surgical condition of the following kind:
- •acute heart failure
- •acute coronary syndrome < 1 month
- •strole < 1 month
- •active pericarditis / myocarditis / endocarditis
- •thromboembolic disease with < 2 weeks of anticoagulation
- •acute infection requiring intravenous treatment
- •ongoing intravenous perfusion
- •surgery < 2 months
- •recent bone fracture
- •Previous episode of primary cardiac arrest (ie, cardiac arrest that did not occur in the presence of an acute myocardial infarction or during a cardiac procedure).
- •Severe heart failure (NYHA III and IV)
- •Severe stenotic or regurgitant valvular disease
- •Uncontrolled hypertension at rest (SBP≥160mmHg, DBP≥100mmHg)
- •Uncontrolled dysrhythmia
- •Non-sustained ventricular tachycardia with exercise
- •Implanted defibrillator
- •Obstructive cardiomyopathy
- •Resting HR > 100/min
- •Severe peripheral artery disease
- •Severe COPD (VEMS < 50%)
- •Exercise-induced asthma
- •Oxygen dependency
- •Muscular-skeletal anomaly that may limit exercise participation
- •Inability to follow instructions
- •Inability to consent
研究组 & 干预措施
Traditionnal rehabilitation
Traditionnal group rehabilitation 3 times a week, 1 hour duration.
干预措施: Traditionnal group rehabilitation (Other)
high intensity interval training-HIIT
HIIT 4 times a week, 30 minutes duration
干预措施: high intensity interval training-HIIT (Other)
结局指标
主要结局
Proportion of patients who complete the rehabilitation program
时间窗: 2 weeks
次要结局
- Distance walked in the 6MWT(2 weeks)
- Muscle strength assessed for the upper and lower extremities(2 weeks)
- Step variability changes as a measure of quality of ambulation(2 weeks)
研究者
Jean-Luc Reny
Head of division, Internal medicine and rehabilitation Trois-Chêne
University Hospital, Geneva