NCT02278016Unknown不适用
Diagnosis Value of Procalcitonin, Interleukin-6, AgiotensininⅡin the Cerebrospinal Fluid of Patients With Central Nervous System Infective Diseases
Xijing Hospital1 个研究点 分布在 1 个国家目标入组 150 人开始时间: 2014年8月最近更新:
适应症
试验速览
- 阶段
- 不适用
- 发起方
- 入组人数
- 150
- 试验地点
- 1
- 主要终点
- Levels of procalcitonin, interleukin-6, agiotensininⅡ in the serum and cerebrospinal fluid
研究概览
简要总结
Bacterial meningitis is a potentially life-threatening disease that is associated with substantial neurological morbidity and mortality. Accurate diagnosis is essential to improve outcome and prevent antibiotic overuse. Here we try to explore new biological markers for the diagnosis of the central nervous system infection disease.
详细描述
To investigate the diagnosis value of procalcitonin,interleukin-6, agiotensininⅡin the cerebrospinal fluid in the central nervous system infection disease.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Only
- 时间视角
- Prospective
入排标准
- 年龄范围
- 13 Years 至 —（Child, Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Aged 13 years or older;
- •At least two of the following clinical characteristics:headache, fever, neck stiffness, mental symptoms or consciousness impairment or seizures
- •Patients' family signed informed consent.
排除标准
- •Contraindications to lumbar puncture
- •Patients with active malignancy
结局指标
主要结局
Levels of procalcitonin, interleukin-6, agiotensininⅡ in the serum and cerebrospinal fluid
时间窗: 36 months
meet the clinical diagnostic criteria for the central nervous system infection disease, the blood and cerebrospinal fluid samples after onset.
次要结局
未报告次要终点
研究者
研究点 (1)
Loading locations...
相似试验
Unknown
不适用
The Role of Serum Procalcitonin in Diagnosis and Detection of Outcome of Acute Bacterial Meningitis in ChildernCNS Infection in ChildrenNCT04929925Sohag University100
已完成
不适用
Diagnostic Performance of Clinical Signs Patients Suspected of Meningitis to EmergenciesMeningitisNCT02841254Nantes University Hospital579
招募中
不适用
National Bacterial Meningitis Study in Children and NewbornsChildren, OnlyPneumococcal Conjugate VaccineMeningitisMeningococcal VaccinesH. Influenzae VaccineNeonatal InfectionAntibiotic TreatmentCase Fatality RateNCT04664569Association Clinique Thérapeutique Infantile du val de Marne10,000
Unknown
不适用
Role of CSF-CRPand Serum Procalcitonin in Differentiation Between Bacterial and Viral Meningitis in ChildrenMeningitis in ChildrenNCT03387969Assiut University80
Unknown
不适用
Validation of a Predictive Rule for the Diagnosis of Viral Meningitis in Adult Emergency DepartmentsMeningitisNCT05062642Centre Hospitalier le Mans1,000