Effects of Exercise Frequency on Muscle Size and Strength in Healthy, Untrained Young Adults
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 发起方
- 入组人数
- 40
- 试验地点
- 2
- 主要终点
- Change in Total Body Skeletal Muscle Mass Measured using the D3-Creatine Dilution Method
研究概览
简要总结
Resistance training (RT) is important for building and maintaining healthy muscles. An exercise frequency called "exercise snacks" involves short bursts of exercise throughout the day (~5-15 minutes), but no studies have examined a gym-based RT exercise snack program. The invetigators will randomize 40 participants into one of two groups for 10 weeks: the control group will complete two full-body workouts per week (standard-frequency) and the experimental group will complete 10 mini-workouts per week (high-frequency). Muscle hypertrophy (size) and strength will be measured before and after the exercise program to determine if the participants had the same or different results.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Basic Science
- 盲法
- None
盲法说明
The person conducting the analysis for cross-sectional area of the muscle ultrasound images will be blinded to participant identity and participant group assignment during this analysis.
入排标准
- 年龄范围
- 19 Years 至 39 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Can fluently read and write in English
- •Lives, works, and/or studies at or near the Gateway Health Building (where all study visits will occur)
- •Willing and able to commit to 2 or 10 in-person training sessions per week for 10 continuous weeks, as well as one week of testing before the training period and one week of testing after the training period
- •Has continuous access to smartphone or other device that they can use to access the Technogym app
- •Answers "No" to all questions on the Canadian Society for Exercise Physiology - Get Active Questonnaire (CSEP-GAQ) or has their doctor's approval to participate
排除标准
- •Any major uncontrolled cardiovascular, muscular, metabolic, and/or neurological disorders
- •Lung disease, kidney disease, or liver disease
- •Current diagnosis of type 1 diabetes, type 2 diabetes, or cancer
- •Medical conditions that limit their ability to undertake strenuous physical activity
- •Regular use of any medications that may affect muscle physiology or body composition (i.e. benzodiazepines, hormone replacement therapy, ADHD medication, Metformin, Ozempic)
- •Participated in consistent resistance exercise training more than twice per month in the previous 12 months
- •Participated in consistent moderate or vigorous aerobic training more than twice per week in the previous 12 months, or planning to start consistent training in the next few months
- •Significant gain or loss of body mass in the past 6 months (greater than 2 kg)
- •Current smoker (including but not limited to cigarettes, e-cigarettes, or vaping)
- •Body Mass Index of less than 18 kg/m2 or over 30 kg/m2
- •Pregnancy or breastfeeding
- •Currently taking blood thinners
- •Allergic to Tegaderm medical tape (used with the activity trackers)
研究组 & 干预措施
Standard-frequency resistance training
干预措施: Two sessions per week of resistance training (Behavioral)
High-frequency resistance training
干预措施: 10 sessions per week of resistance training (Behavioral)
结局指标
主要结局
Change in Total Body Skeletal Muscle Mass Measured using the D3-Creatine Dilution Method
时间窗: From enrolment (Week 1) to the end of the exercise training phase (Week 12)
次要结局
- Change in Total Body Muscle Size Measured as Cross-sectional Area using Muscle Ultrasound Imaging(From enrolment (Week 1) to the end of the exercise training phase (Week 12))
- Change in Muscle Strength Measured as the One-Repetition Maximum of Back Squat and Bench Press(From enrolment (Week 1) to the end of the exercise training phase (Week 12))
- Change in Skeletal Muscle Power Measured at Various Relative Loads for Back Squat and Bench Press(From enrolment (Week 1) to the end of the exercise training phase (Week 12))
- Participant Satisfaction with the Exercise Program(At the end of the exercise training phase (Week 12))
研究者
Cameron Mitchell
Associate Professor
University of British Columbia