The Effect of Ordered Eating on Postprandial Glucose and Substrate Utilization During an Acute Exercise Bout
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 23
- 试验地点
- 2
- 主要终点
- Postprandial glucose
研究概览
简要总结
There is well documented evidence that ingesting dietary carbohydrate in large amounts tends to increase postprandial glucose. In healthy populations, this is not necessarily a problem, but continuous exposure to high levels of glucose-hyperglycemia-is a defining characteristic and risk factor for type 2 diabetes mellitus. Consuming a carbohydrate-rich food as the final food in a meal sequence has been shown to significantly reduce postprandial glucose excursions in both diabetes patients and in healthy controls. The exact mechanisms behind this phenomenon are not well understood, but one proposed course is simply that the vegetable and protein already being digested slows the rate of glucose rise.
Despite the findings, little-to-no research has examined how manipulating the order of foods in a meal impacts subsequent exercise responses. In this experimental crossover study, each participant will undergo two acute feeding conditions (carbohydrate-rich foods first vs. last in a meal), which will be followed by exercise 60 minutes later. We will observe the effects of meal order on postprandial glucose, substrate/fuel utilization, and subjective perceptions at rest and during 30 minutes of exercise.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Crossover
- 主要目的
- Basic Science
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 60 Years(Adult)
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Currently physically active (scheduled exercise at least three days per week for 30 minutes each time over the last three months)
- •Ability to perform moderate-to-high intensity running for at least 30 minutes
排除标准
- •Any allergy or other condition that would prohibit the consumption of poultry, rice, or broccoli
- •Any injury or disease (cardiovascular disease, diabetes, pulmonary disease except controlled asthma) precluding physical exercise
- •Currently pregnant
- •Implanted electrical devices such as a pacemaker.
研究组 & 干预措施
Carbohydrate-first meal
干预措施: Carbohydrate-first meal (Other)
Carbohydrate-last meal
干预措施: Carbohydrate-last meal (Other)
结局指标
主要结局
Postprandial glucose
时间窗: 2 hours (premeal and 30, 60, 90, and 120 minutes after eating)
Blood glucose will be measured with fingerstick samples and a portable glucometer
次要结局
- Hunger-satiety perceptions(2 hours (Premeal and at 15, 30, 45, 60, 68, 78, 88, 120 minutes after eating))
- Carbohydrate use(100 minutes (premeal and continuously for 90 minutes after eating))
- Fat use(100 minutes (premeal and continuously for 90 minutes after eating))
- Rating of perceived exertion(30 minutes (at 8, 18, 28 minutes of exercise))
研究者
Patrick Wilson, PhD
Associate Professor of Exercise Science
Old Dominion University
