ITMCTR2024000021尚未招募Unknown
The effect of acupuncture pretreatment on the clinical pregnancy rate of IVF-ET in patients with diminished ovarian reserve: a multicenter randomized controlled trial
Institute of Acupuncture and Moxibustion, China Academy of Chinese Medical Sciences0 个研究点开始时间: 待定最近更新:
适应症
试验速览
- 阶段
- Unknown
- 状态
- 尚未招募
- 发起方
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
- 年龄范围
- 20 至 40（—）
- 性别
- Female
入选标准
- •(1) Meets the criteria for Group 3 and Group 4 of the POSEIDON POR classification criteria;
- •(2) Female, 20 years = age < 40 years;
- •(3) Regular menstruation (21-35 days);
- •(4) Fertility needs, with a proposed IVF/ICSI-ET antagonist or microstimulation regimen to assist conception, and with a proposed transfer of 1-2 high-quality embryos at the cleavage stage or 1 blastocyst;
- •(5) Voluntarily participate in the trial and sign the informed consent form.
排除标准
- •(1) FSH = 25 IU/L;
- •(2) Diseases related to the reproductive physician's judgment that affect conception (any of the following may be excluded if they do not affect embryo transfer): congenital abnormalities in the development of reproductive organs, untreated endometrial polyps, untreated uterine adhesions, untreated uterine infections, untreated tubal hydrosalpinx, thin endometrium, uterine fibroids (>5 cm, submucosal uterine fibroids), endometriosis, or other organic diseases;
- •(3) Repeated implantation failures (after at least 3 transfer cycles, fresh or frozen embryo transfer cycles involving the transfer of at least 4 high-quality embryos without pregnancy; or 2 consecutive fresh or frozen transfer cycles and the transfer of at least 4 cleavage-stage embryos or at least 2 high-quality blastocysts without obtaining a clinical pregnancy);
- •(4) Combination of metabolic endocrine diseases such as uncorrected hyperprolactinemia, hyperandrogenemia, thyroid dysfunction, chronic hypoadrenocorticism, or other metabolic endocrine diseases;
- •(5) Azoospermia in the male partner;
- •(6) Those with combined serious cardiovascular, cerebrovascular, hepatic, renal, malignant tumor, hematopoietic system and mental diseases;
- •(7) Those who have a history of acupuncture treatment;
- •(8) Recurrent abortion (refers to 2 or more consecutive pregnancy losses with the same spouse that occurred before 28 weeks of gestation, including biochemical pregnancy);
- •(9) Patients with severe anxiety, i.e., those with a score of >70 on the Self-Rating Anxiety Scale (SAS);
- •(10) Chromosomal abnormalities and carriers.
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