Impact of Obesity on Textbook Outcome Achievement in Minimally Invasive Colorectal Cancer Surgery
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 305
- 试验地点
- 1
- 主要终点
- Demographic, clinical, and perioperative characteristics
研究概览
简要总结
Textbook Outcome (TO) is a composite quality measure that integrates multiple perioperative endpoints to provide a comprehensive assessment of surgical quality. Although obesity has been associated with adverse outcomes after colorectal surgery, its impact on achieving TO remains unclear, particularly in the era of minimally invasive surgery. This study aimed to evaluate the association between body mass index (BMI) and TO achievement in patients undergoing minimally invasive colorectal cancer surgery.
详细描述
This retrospective observational study aims to evaluate the association between body mass index (BMI) and achievement of Textbook Outcome (TO) in patients undergoing minimally invasive colorectal cancer surgery. Patients who underwent curative minimally invasive colorectal cancer resection at a single tertiary referral center between 2021 and 2025 will be retrospectively evaluated. Patients will be categorized according to BMI as non-obese (BMI <30 kg/m²) and obese (BMI ≥30 kg/m²). Textbook Outcome will be assessed as a composite measure including R0 resection, retrieval of at least 12 lymph nodes, absence of major postoperative complications (Clavien-Dindo grade ≥IIIa), hospital stay ≤14 days, absence of 30-day readmission, and absence of 30-day mortality. The study will investigate whether BMI is associated with failure to achieve Textbook Outcome and will evaluate independent predictors of TO failure using multivariable logistic regression analysis.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Retrospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients who underwent curative minimally invasive colorectal cancer resection at a single tertiary referral center between 2021 and 2025 were retrospectively reviewed. All patients were ≥18 years of age.
排除标准
- •Patients undergoing metastatic resections, abdominoperineal resection (APR), Hartmann's procedure, multisegmental or total colectomy, transanal minimally invasive surgery (TAMIS), or palliative procedures were excluded from the analysis.
研究组 & 干预措施
non-obese grup
BMI <30 kg/m²
obese group
BMI ≥30 kg/m²
结局指标
主要结局
Demographic, clinical, and perioperative characteristics
时间窗: 30 days
Age, sex, comorbidity burden assessed by the age-adjusted Charlson Comorbidity Index (CCI) , ASA score , tumor location, neoadjuvant therapy, surgical approach, or postoperative complication rates
次要结局
- Textbook Outcome(30 days)