NCT03025997已完成不适用
The Effect of Orally Applied Encapsulated Lipids in Yoghurt on Satiety and Food Intake: a Randomized Single-blind Placebo-controlled Study With Cross-over Design
适应症
干预措施
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 33
- 试验地点
- 1
- 主要终点
- ad libitum food intake
研究概览
简要总结
This study evaluates the ability of encapsulation of orally applied lipids in a yoghurt snack to modify ad libitum food intake and satiety, without GI symptoms. Every subject receives two treatments (active, and placebo) on two different days, following a randomized cross-over design.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Crossover
- 主要目的
- Prevention
- 盲法
- Single (Participant)
入排标准
- 年龄范围
- 18 Years 至 65 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •BMI between 25-30 kg/m2
- •Voluntary participation
排除标准
- •Milk (-protein or lactose)- allergy/intolerance
- •History of serious GI complaints/surgeries
- •Pregnancy, lactation
- •Excessive alcohol consumption (>20 per week)
- •Abnormal eating behaviour
- •Intention to stop smoking
- •Reported unexplained weight loss or gain in the month prior to screening
- •Self-admitted HIV-positive state
研究组 & 干预措施
Active yoghurt
Active Comparator
Yoghurt snack containing encapsulated lipid
干预措施: Active yoghurt (Dietary Supplement)
Placebo yoghurt
Placebo Comparator
Yoghurt snack containing non-encapsulated lipid
- empty encapsulation matrix
干预措施: Placebo yoghurt (Dietary Supplement)
结局指标
主要结局
ad libitum food intake
时间窗: 2 hours after yoghurt snack
t=0: standardized breakfast, t=90 minutes: yoghurt, t=210 minutes: ad libitum food intake
次要结局
- Satiety feelings(Up to 3.5 hours on each of the 2 test days.)
- occurrence and severity of GI symptoms(Up to 3.5 hours on each of the 2 test days.)
研究者
研究点 (1)
Loading locations...
相似试验
已完成
2 期
The effect of orally applied encapsulated lipids in yoghurt on satiety and food intake: a randomized single-blind study with cross-over desigoverweight10003018obesityNL-OMON43311niversiteit Maastricht35
已完成
2 期
Efficacy of Cardioviva™ Probiotic Yogurt FormulationHypercholesterolemiaNCT01185795Micropharma Limited150
已完成
不适用
The Effect of Different States of Lipid in Food on Glycaemia, Lipaemia and Insulinaemia.Cardiovascular Risk FactorDiabetes Mellitus, Type 2NCT04115592Clinical Nutrition Research Centre, Singapore19
进行中（未招募）
1 期
Influence of lipid emulsions for parenteral nutrition on the fonctional state of cutaneous barrierEUCTR2013-005619-28-FRHospices Civils de Lyon40
已完成
不适用
Eggshell Membrane Beauty From Within TrialSkin ElasticitySkin HydrationSkin Barrier to Water LossFingernail HealthHair HealthNCT06148337ESM Technologies, LLC63