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临床试验/NCT04424849
NCT04424849Unknown不适用

Initial Thoracic CT Findings and Mechanical Ventilation Requirement in Patients Admitted to Intensive Care Unit With COVID-19

Tepecik Training and Research Hospital1 个研究点 分布在 1 个国家目标入组 40 人开始时间: 2020年3月15日最近更新:
适应症

试验速览

阶段
不适用
发起方
入组人数
40
试验地点
1
主要终点
Invasive respiratory support in patients with COVID-19

研究概览

简要总结

The most common thorax Computed tomography (CT) findings are multifocal ground-glass opacities and peripheral consolidation in patients with COVID-19. Septal thickening, bronchiectasis, pleural thickening, and subpleural involvement may also be observed. Although these findings are not specific to COVID-19, the severity of pulmonary involvement is expected to be correlated with thorax CT findings.

详细描述

Thorax computed tomography severity score defined by Yang et al. can be used to evaluate the severity of pulmonary involvement in COVID-19 patients. We aimed to investigate whether the initial thorax computed tomography severity score can predict mechanical ventilation requirement and mortality in COVID-19 patients.

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Retrospective

入排标准

年龄范围
18 Years 至 —(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • Age ≥ 18 years
  • COVID-19 confirmed by positive RT-PCR and/or antibody testing
  • CT scan at intensive care unit admission

排除标准

  • Loss of CT data
  • Chronic lung disease findings by CT that may lead to misinterpretation
  • RT-PCR results unavailable or negative
  • Terminal cancer

结局指标

主要结局

Invasive respiratory support in patients with COVID-19

时间窗: 120 days

Whether Thorax CT findings predict invasive mechanical ventilation requirement of covid-19 patients

次要结局

  • Mortality in patients with COVID-19(120 days)

研究者

发起方
Tepecik Training and Research Hospital
申办方类型
Other
责任方
Principal Investigator
主要研究者

Kazim Rollas

MD

Tepecik Training and Research Hospital

研究点 (1)

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