Comparison of the diagnostic accuracy of velocity time integral of left ventricular outflow tract and stroke volume variation in predicting fluid responsiveness in paediatric cardiac surgery patients in post operative ICU care
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 入组人数
- 66
- 试验地点
- 1
- 主要终点
- To find sensitivity, specificity, positive predictive and negative predictive value of LVOT VTI in prediction fluid responsiveness.
研究概览
简要总结
All patients who will undergo elective cardiac surgery between the ages of 1 and 18years are to be enrolled in the study. Patients with open chest, arrhythmias and shunts are to be excluded. In all patients arterial line to be inserted, either femoral or radial, and will be connected to the MostCare Up monitor for SVV and BP monitoring. SVV and LVOT VTI variability to be measured once at arrival in post operative ICU care. Based on the cut off values of 10% and 12 %, respectively for SVV and LVOT VTS variability, patients to be divided into fluid responsive and non responders. If responsive, a fluid challenge of of 10ml/kg of crystalloids to be given over 20 minutes and values to be recorded again. If patient is still responsive another bonus is to be given.
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 1.00 Year(s) 至 18.00 Year(s)（—）
- 性别
- All
入选标准
- •Patients undergoing elective cardiac surgery.
- •Age – 1 to 18 years old.
排除标准
- •patients with open chest, arrhythmias and shunts 2) patients with weight less than 3 kg.
结局指标
主要结局
To find sensitivity, specificity, positive predictive and negative predictive value of LVOT VTI in prediction fluid responsiveness.
时间窗: Baseline, post operative day 0
次要结局
- 1. To compare the correlation of VTI-LVOT variability with stroke volume variation (SVV) from arterial pulse pressure recording analytical method (PRAM) for prediction of fluid responsiveness in paediatric patients undergoing cardiac surgery(2. To find the sensitivity, specificity, positive & negative predictive value of LVOT-VTI variability in predicting fluid responsiveness.)
研究者
Dr Manoj Kamal
AIIMS Jodhpur