Examine the Effect of Repetitive Transcranial Magnetic Stimulation (rTMS) Over the Symptoms of Autism Spectrum Disorder
试验速览
- 阶段
- 1 期
- 发起方
- 入组人数
- 30
- 试验地点
- 1
- 主要终点
- continuous performance test
研究概览
简要总结
rTMS over dorsolateral prefrontal cortex is effective in reducing repetitive behaviors in adults with autistic spectrum disorder rTMS over posterior superior temporal sulcus is effective in improving social ability in adults with autistic spectrum disorder
详细描述
First, we will apply one session intermittent theta burst stimulation over dorsolateral prefrontal cortex, posterior superior temporal sulcus and inion as control with one week interval in adults with autism spectrum disorder. Second, we will apply 5 sessions intermittent theta burst stimulation within one week over dorsolateral prefrontal cortex or posterior temporal sulcus depending on the results of our first phases.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 40 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •adults with autistic spectrum disorder
排除标准
- •schizophrenia
- •bipolar affective disorder
- •major depressive disorder
- •any systemic disease especially epilepsy
结局指标
主要结局
continuous performance test
时间窗: continuous performance test will be arranged before and after rTMS within one hour
continuous performance test will be arranged before and after rTMS within one hour
次要结局
- Yale-Brown Obsessive Compulsive Scale(Yale-Brown Obsessive Compulsive Scale will be evaluated before and after rTMS within one week)