Effectiveness of Using Nano-Silver Fluoride Varnish Versus Sodium Fluoride Varnish in Management of Cervical Dentin Hypersensitivity in Adult Patients: A Randomized Clinical Trial.
试验速览
- 阶段
- 不适用
- 发起方
- 入组人数
- 42
- 主要终点
- change in dentin Hypersensitivity
研究概览
简要总结
2 different varnishes will be used to test their effectiveness in controlling teeth hypersensitivity in adult patient.
详细描述
In-vivo part:
Each varnish will be applied separately on different teeth according to the manufacturer's instructions and the VAS will be measured according to a specific timeline: T0 (baseline, before application of varnish), T1 (1 week after application), T2 (4 weeks after application) and T3 (4 weeks after application).
In-situ part:
Dentin specimen will be prepared from extracted teeth from the orthodontic department in our college, sterilized and prepared.
it will be bonded to an orthodontic wire and bonded to upper first molar. Dentinal occlusion will be measured using scanning electron microscope following the same timeline.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Triple (Participant, Care Provider, Outcomes Assessor)
入排标准
- 年龄范围
- 25 Years 至 50 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Patients consulting in one of the Qasr Einy, faculty of dentistry outpatient clinics.
- •Males or females.
- •Patient's age range 25-50 years.
- •Patients complaining of hypersensitive areas on facial surfaces of the teeth (incisors, cuspids, bi-cuspids, and first molars with exposed cervical dentine) with teeth scoring Bpain (VAS score: greater than or equal to 3) during application of stimulus (airblast and tactile sensitivity test).
- •Tooth with exposed root surface, complaining from hypersensitivity (VAS score; greater than or equal to 3).
- •Patients accept the 2-months follow-up period.
- •Provide informed consent.
排除标准
- •• Patients participating in another dental study that may alter the results of this study.
- •A medical condition that could hinder the accuracy of pain reporting (e.g., pain disorders).
- •Any chronic medical condition that requires the regular use of anti-inflammatory pain medications.
- •Patients used or applied a desensitizing varnish within the last four weeks.
- •Patients with dental problems; chipped teeth, defective restorations, fractured Un-displaced cuspids or deep dental caries.
- •Lack of patient's approval and compliance.
结局指标
主要结局
change in dentin Hypersensitivity
时间窗: 1 week, 4 weeks & 8 weeks
Visual Analogue Scale (VAS) will be used; 0 is no pain and 10 is severe pain. Pictures are added to the same, as well as colors to guide the patient during selection of pain severity.
次要结局
- change in dentinal Tubule Occlusion(1 week, 4 weeks * 8 weeks)
研究者
Nayera Hassanien Mohamed
Assistant Lecturer
Cairo University