Delivery Method and Risk for Urogenital Prolapse 15-20 Years Later
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 1,641
- 试验地点
- 1
- 主要终点
- symptoms of urogenital prolapse
研究概览
简要总结
The lifetime risk for a woman to undergo surgery for either vaginal prolapse or urinary incontinence is high. Previous studies have shown that pregnancy and childbirth are risk factors for developing prolapse. There is a lack of studies that follow women several years after delivery aiming to find whether symptoms of prolapse are linked to delivery method, ie vacuum, forceps, normal vaginal delivery and cesarean section. The investigators plan this study is to get more knowledge about pathology of prolapse and incontinence, to enable development of preventive strategies for these conditions.
Aim of the study is to determine whether the prevalence of symptoms and performed surgery for urogenital prolapse differs among women delivered by vacuum, forceps, normal vaginal delivery and cesarean section 15-20 years after their first delivery.
The investigators identify women that delivered their first child at St. Olavs Hospital, Trondheim, Norway between 1990-1997. Questionnaires will be sent to 2500 women (PFIQ-7, PFDI-20, PISQ-12), 600 of whom will get a clinical examination, where pelvic floor musculature is examined by palpation and 4D ultrasound, and a POP-Q quantification of prolapse performed.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Retrospective
入排标准
- 年龄范围
- 40 Years 至 60 Years(Adult)
- 性别
- Female
- 接受健康志愿者
- 否
入选标准
- •first delivery in time period 1990-1997
- •vaginal birth, spontaneous, forceps or vacuum extraction, or cesarean section
- •residency in Klæbu, Malvik, Melhus, Midtre Gauldal, Rissa, Selbu, Trondheim, Tydal, Åfjord at the time of first delivery
排除标准
- •stillbirth
- •breech birth
- •congenital Abnormalities
- •residency outside the 9 selected communities
- •forceps delivery following previous vacuum extraction delivery or spontaneous vaginal birth
- •vacuum extraction delivery following previous forceps delivery or spontaneous vaginal birth
- •Vaginal birth following previous cesarean section
结局指标
主要结局
symptoms of urogenital prolapse
时间窗: 15-20 years after first delivery
surgery for urogenital prolapse
时间窗: 15-20 years after first delivery
次要结局
- damage to pelvic floor musculature(15-20 years after first delivery)
- anal incontinence(15-20 years after first delivery)
- urinary incontinence(15-20 years after first delivery)
