NCT00976274已完成不适用
Effects of Korean Red Ginseng on Cardiovascular Risks in Subjects With Metabolic Syndrome
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 60
- 试验地点
- 2
- 主要终点
- Change in the Pre- and Post-treatment Systolic Blood Pressure
研究概览
简要总结
Five factor consisting of Metabolic syndrome is closely linked by insulin resistance. Until now, several studies have been performed about effects of Korea red ginseng on hypertension, diabetes, and hyperlipidemia, but not metabolic syndrome.
The investigators hypothesize that Korean red ginseng could improve each constituents of metabolic syndrome, arterial stiffness, and inflammatory markers.
The aim of this study is to determine effects of Korean red ginseng on cardiovascular risks in subjects with metabolic syndrome.
详细描述
The details of study objective are followed by these:
- comparison of blood pressure before and after Korean red ginseng administration
- comparison of metabolic indicator before and after Korean red ginseng administration
- comparison of oxidative stress and inflammatory markers before and after Korean red ginseng administration
- comparison of arterial stiffness before and after Korean red ginseng administration
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Triple (Participant, Care Provider, Investigator)
入排标准
- 年龄范围
- 20 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •(three or more of following five factors)
- •waist circumference(male: more than 90cm, female: more than 80cm)
- •blood pressure(systolic: more than 130mmHg, diastolic: more than 85mmHg)
- •fasting plasma glucose: more than 100mg/dL
- •fasting triglycerides: more than 150mg/dL
- •High-density lipoprotein(HDL)-cholesterol(male: less than 40mg/dL, female: less than 50mg/dL)
排除标准
- •(any one of following factors)
- •uncontrolled blood pressure(systolic: more than 160mmHg, diastolic: more than 100mmHg) or subjects taking blood pressure lowering drug
- •Type 2 diabetes patients or fasting plasma glucose more than 126mg/dL
- •triglyceride more than 400mg/dL, total cholesterol more than 250mg/dL
- •subjects taking antilipidemic drug
- •past history of coronary heart disease or cerebrovascular disease
结局指标
主要结局
Change in the Pre- and Post-treatment Systolic Blood Pressure
时间窗: baseline and 12 weeks
次要结局
- Change in the Pre- and Post-treatment Oxidized Low-densty Lipoprotein(LDL)(baseline and 12 weeks)
研究者
Jae-Yong Shim
Professor
The Korean Society of Ginseng
研究点 (2)
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