A study comparing effects of fentanil vs dexmedetomidine for smooth and efficient extubation
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 发起方
- 入组人数
- 90
- 试验地点
- 1
- 主要终点
- To evaluate the impacts of fentanil and dexmedetomidine on heart rate and systolic blood pressure and diastolic blood pressure , mean arterial pressure during extubation
研究概览
简要总结
A study comparing effects of fentanil vs dexmedetomidine for smooth and efficient extubation undergoing different elective surgeries under general anaesthesia will be conducted in department of anaesthesia.
Varun Arjun medical college and rohilkhand hospital, banthara, Shahjahanpur, Uttar Pradesh, 242307, focusing on extubation undergoing different elective surgeries under general anaesthesia.
A. This study will involve patients scheduled for elective surgeries requiring general anaesthesia based on specific inclusion and exclusion criteria.
B. Each patient will undergo a thorough medical history review and provide written informed consent.
C. Participants will undergo preoperative and clinical and laboratory assessment.
D. Patients will be admitted one day prior to the surgery.
E. Participants will be randomly allocated into two groups (ns=30)
Group-F will receive 1mcg/kg fentanil.
Group-D will receive 0.5mcg/kg dexmedetomidine
Group-NS will receive 100ml NS
F. This study will evaluate and contrast the impacts of fentanyl and dexmedetomidine data on heart rate and systolic blood pressure and diastolic blood pressure, mean arterial pressure during extubation to compare the the quality of extubation will be collected throughout the study
研究设计
- 研究类型
- Interventional
- 分配方式
- Other
- 盲法
- None
入排标准
- 年龄范围
- 18.00 Year(s) 至 60.00 Year(s)（—）
- 性别
- All
入选标准
- •ASA GRADE I& II Normotensive patients Age between 18-60 years.
排除标准
- •Unwilling patients Patients with past h/o Myocardial ischemia, Hypertension, CVA Individuals experiencing a current upper respiratory tract infection Patients with anticipated difficult intubation.
- •Patients having cardiac, pulmonary, hepatic and renal diseases.
- •Patients with ASA GRADE more than III.
结局指标
主要结局
To evaluate the impacts of fentanil and dexmedetomidine on heart rate and systolic blood pressure and diastolic blood pressure , mean arterial pressure during extubation
时间窗: To evaluate the impacts of fentanil and dexmedetomidine on heart rate and systolic blood pressure and diastolic blood pressure , mean arterial pressure during extubation will be done for 1 year
次要结局
- To evaluate quality of extubation & postoperative sedation with fentanil or dexmedetomidine(To evaluate the impacts of fentanil & dexmedetomidine on heart rate & systolic blood pressure & diastolic blood pressure , mean arterial pressure during extubation for 1 year)
研究者
Dr Vadde naveen chandra
Varun arjun medical college and rohilkhand hospital