Evaluation and Validation of Biological Age as Health Technology
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 83
- 试验地点
- 2
- 主要终点
- Change in biological age
研究概览
简要总结
In a previous study the investigators have developed a novel biological age model. Assessing biological age is the assessment of the present health status and functional capacity/physiological reserve of that person in comparison with people of the same age and sex.
The aim of this study is to investigate the utility and validity of this novel biological age model designed for health promotion in real world conditions.
详细描述
Study design: This is a longitudinal study, where biological age assessment is conducted in the first and final week of an 11-14 week lifestyle intervention course. These courses take place at a Danish folk high school (Ubberup), which is specialized in performing intensive lifestyle interventions targeting a 10% weight loss. The intention is to include 80 adult men and women.
Data collection: This will take place at the facilities at Ubberup folk high school, participants being overnight fasted and without having exercised for the previous 24 hours. All analysis will be performed in investigators lab (Xlab) at the Department of Biomedical Sciences, Copenhagen University. When all samples are analysed Biological age will be calculated for each particpant.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 65 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Participation in a long course at Ubberup folk high school (12-15 weeks)
- •Age between 18-65 years
排除标准
- •Previous or current cardiovascular disease
- •Pregnancy
- •Conditions that prevents from performing a cycle and/or strength tests
结局指标
主要结局
Change in biological age
时间窗: week1 and week 14
a composite score predicting risk of lifestyle related diseases
次要结局
- Change in Respirometry(week 1 and week 14)
- Change in cardiorespiratory capacity(week 1 and week 14)
- Change in strength(week 1 and week 14)
- Change in Sit to Stand test(week 1 and week 14)
- Change in Central obesity(week 1 and week 14)
- Change in body weight(week 1 and week 14)
- Change in body composition(week 1 and week 14)
- Change in fat mass(week 1 and week 14)
- Change in Hormones(Week 1 and week 14)
- Change in fat percentage(week 1 and week 14)
- Change in lipid profile(week 1 and week 14)
- Change in muscle mass(week 1 and week 14)
- Change in Inflammatory profile(week 1 and week 14)
- Change in Blood glucose(week 1 and week 14)
- Change in Blood Pressure(week 1 and week 14)
- Change in Advanced glycation endproducts(week 1 and week 14)
研究者
Jørn Wulff Helge
Proffesor Jørn Wulff Helge
University of Copenhagen