SYMPHONY (SYMptoms and PHysiology to Observe and uNderstand activitY): Using continuous, passive, non-invasive wearable technology to understand the interactions between physiology, behaviour, the environment and exacerbations of chronic obstructive pulmonary disease (COPD)

niversity of Leicester0 个研究点目标入组 100 人开始时间: 2019年3月27日最近更新: 2024年4月22日

试验速览

2022 Interim results article in https://pubmed.ncbi.nlm.nih.gov/35473718/ Proof of concept (added 27/10/2022) 2022 Results article in https://pubmed.ncbi.nlm.nih.gov/35171101/ (added 08/04/2024)

•Acute group:
•1. Willing and able to give informed consent for participation in the study
•2. Aged =40 years
•3. Medical Research Council (MRC) grade 2-5 when stable
•4. Able (in the opinion of the COPD Specialist Nurses) and willing to comply with all study requirements
•Stable group:
•1. Willing and able to give informed consent for participation in the study
•2. Aged =40 years
•3. Confirmed diagnosis of COPD
•4. Medical Research Council (MRC) grade 2-5 when stable
•5. Attendance to pulmonary rehabilitation assessment visit
•6. Able (in the opinion of the Pulmonary Rehabilitation assessor) and willing to comply with all study requirements

•All participants:
•1. Female participants who are pregnant or lactating
•2. Any other significant disease or disorder which, in the opinion of the Investigator, may either put the participants at risk because of participation in the study, or may influence the result of the study, or the participant’s ability to participate in the study
•3. Unable or unwilling to comply with study requirements
•4. Inability to take part in light intensity physical activity due to significant mobility issues (e.g. neurological/musculoskeletal disorder)
•Acute group only:
•1. Diagnosis of any other chronic respiratory condition as the primary cause of their hospital admission

发起方

niversity of Leicester