Prognostic Value of Oscillatory Pattern of Sympathetic Nerve Activity Muscle in Patients With Heart Failure

University of Sao Paulo General Hospital1 site in 1 country160 target enrollmentOctober 2013

ConditionsHeart Failure

Overview

Phase: Not Applicable
Intervention: Not specified
Conditions: Heart Failure
Sponsor: University of Sao Paulo General Hospital
Enrollment: 160
Locations: 1
Primary Endpoint: Peripheral autonomic control
Last Updated: 10 years ago

Overview Investigators Eligibility Criteria Outcomes Sites Similar Trials

Overview

Brief Summary

The purpose of this study is to determine whether oscillatory pattern of sympathetic nerve activity muscle is an efficient index for the prognosis of patients with heart failure.

Registry

clinicaltrials.gov

Start Date

October 2013

End Date

October 2016

Last Updated

10 years ago

Study Type

Observational

Sex

All

Investigators

Sponsor

University of Sao Paulo General Hospital

Responsible Party

Sponsor

Eligibility Criteria

Inclusion Criteria

•Patients with systolic heart failure and New York Heart Association (NYHA)
•Ischemic, hypertensive, or idiopathic etiology
•Left ventricular ejection fraction less than 40%

Exclusion Criteria

•Neuromuscular, Orthopedic, Neurologic and Pulmonary Diseases
•Renal failure
•Diabetes mellitus type II

Outcomes

Primary Outcomes

Peripheral autonomic control

Time Frame: 12 months

Evaluate if the reduction in the oscillatory pattern of muscle sympathetic nerve activity is associated with morbidity and mortality in patients with heart failure in a clinical follow-up 12 months