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临床试验/NCT02047409
NCT02047409Unknown不适用

Prognostic Value of Oscillatory Pattern of Sympathetic Nerve Activity Muscle in Patients With Heart Failure

University of Sao Paulo General Hospital1 个研究点 分布在 1 个国家目标入组 160 人开始时间: 2013年10月最近更新:
适应症

试验速览

阶段
不适用
入组人数
160
试验地点
1
主要终点
Peripheral autonomic control

研究概览

简要总结

The purpose of this study is to determine whether oscillatory pattern of sympathetic nerve activity muscle is an efficient index for the prognosis of patients with heart failure.

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Prospective

入排标准

年龄范围
30 Years 至 65 Years(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • Patients with systolic heart failure and New York Heart Association (NYHA)
  • Ischemic, hypertensive, or idiopathic etiology
  • Left ventricular ejection fraction less than 40%

排除标准

  • Neuromuscular, Orthopedic, Neurologic and Pulmonary Diseases
  • Renal failure
  • Diabetes mellitus type II

结局指标

主要结局

Peripheral autonomic control

时间窗: 12 months

Evaluate if the reduction in the oscillatory pattern of muscle sympathetic nerve activity is associated with morbidity and mortality in patients with heart failure in a clinical follow-up 12 months

次要结局

  • Blood inflammatory markers(12 months)
  • Functional Capacity(12 months)
  • Arterial baroreflex control(12 months)
  • Cardiac and peripheral autonomic control(12 months)

研究者

申办方类型
Other
责任方
Sponsor

研究点 (1)

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