Cohort of Patients With Chronic Myelomonocytic Leukemia
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 5,000
- 试验地点
- 24
- 主要终点
- Understanding the pathophysiology of chronic myelomonocytic leukaemia
研究概览
简要总结
A prospective, non-interventional study involving the collection of biological samples with associated anonymised data.
Biological samples will be collected at the time of diagnosis and/or as the disease progresses, with or without treatment, always in conjunction with tests scheduled as part of routine care or within the context of a clinical trial.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Adults aged 18 years and over
- •Blood monocytosis ≥ 0.5 × 10⁹/L and ≥ 10% of total white blood cells or
- •Confirmed diagnosis of chronic myelomonocytic leukemia
- •Regardless of stage (chronic or transformed), and whether or not currently being treated
- •Signed informed consent
排除标准
- •Active, uncontrolled infection (particularly hepatitis B, hepatitis C, HIV)
- •Refusal informed consent
研究组 & 干预措施
Cohort of patients with chronic myelomonocytic leukemia
干预措施: Sampling (Biological)
结局指标
主要结局
Understanding the pathophysiology of chronic myelomonocytic leukaemia
时间窗: through study completion, an average of 15 years
optimise diagnosis, improve prognostic stratification, identify new treatment options and assess patients' response to proposed treatments through the analysis of blood or bone marrow samples collected as part of routine care or clinical trials
次要结局
未报告次要终点