A Retrospective Study on Laser Treatment of Nevus of Ota in Thai Patients
试验速览
- 阶段
- 不适用
- 入组人数
- 79
- 试验地点
- 1
- 主要终点
- Efficacy of laser treatment in paitients with Nevus of Ota
研究概览
简要总结
A retrospective study on efficacy and complication of laser treatment (Q-switched Nd:YAG and picosecond laser) of nevus of Ota in Thai patients
详细描述
Nevus of Ota is a benign dermal melanocytic nevus found most commonly in Asians. About 50-60% of all cases have the age of onset at birth or within the first year of life, others appear before puberty. It typically presents as a unilateral mottled blue-gray macules and patches distributed along the first and second branches of trigeminal nerve. Due to its marked hyperpigmentation on the face which does not resolved spontaneously, patients may experience psychosocial disturbances and often seek for treatments. Based on selective photothermolysis theory, Q-switched lasers (ruby 694nm, alexandrite 755nm, Nd:YAG 1064nm) have been used for the treatment of nevus of Ota with a success rate of 95% after 6-8 sessions. Reported complications from the lasers are hypopigmentation(15.3%), hyperpigmentation(2.9%), texture changes (2.9%), and scarring (1.9%). Siriraj Skin Laser Center provides laser treatment for nevus of Ota using mainly Q-switched Nd:YAG laser and Picosecond laser. The study of efficacy and complications of Q-switched Nd:YAG and Picosecond laser in the treatment of Nevus of Ota in Thai patients has never been reported. Therefore, we conduct a retrospective study on efficacy and complication of laser treatment (Q-switched Nd:YAG and picosecond laser) of nevus of Ota in Thai patients.
研究设计
- 研究类型
- Observational
- 观察模型
- Other
- 时间视角
- Retrospective
入排标准
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patient with Nevus of Ota
- •Complete data between January 2008 - December 2018
排除标准
- •Incomplete data
结局指标
主要结局
Efficacy of laser treatment in paitients with Nevus of Ota
时间窗: 2008-2018
Fading of lesions after treatment by chart review
次要结局
- Complication of laser such as hyperpigmentation, hypopigmentation, and scars(2008-2018)
- Relapse rate after laser treatment(2008-2018)
研究者
Woraphong Manuskiatti, M.D.
Professor
Mahidol University
