Evaluation of Biological Markers of Mesenteric Ischemia During an Ultra-trail
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 200
- 试验地点
- 1
- 主要终点
- Assess biological markers of mesenteric ischemia (IFABP)
研究概览
简要总结
To assess the evolution of biological markers of mesenteric ischemia during ultratrail.
详细描述
During physical exercise, increased sympathetic nervous system activity redistributes blood flow from splanchnic organs to working muscles. With prolonged duration and / or intensity, the splanchnic blood flow can be reduced by 80% or more. A severely reduced of splanchnic blood flow can frequently cause gastrointestinal ischemia. This ischemia associated with reduced vagal activity probably results in changes in motility and absorption.
High symptoms are reported in 40% of runners with reflux and heartburn in 15-20% of runners. The low symptoms have an incidence of about 70% in the long runs type ultra-trail.
Biological markers such as I-FABP have been shown to be useful in the diagnosis of mesenteric ischemia.
研究设计
- 研究类型
- Observational
- 观察模型
- Other
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Healthy Voluntary Subject
- •Age > 18 years
- •Written consent
- •Subject affiliated to Social Security
- •Medical certificate (mandatory to take part in the ultra-trail)
排除标准
- •Refusal to participate
- •Subject with legal protection (guardianship, trusteeship)
结局指标
主要结局
Assess biological markers of mesenteric ischemia (IFABP)
时间窗: at day 1
during ultratrail.
次要结局
- Relationship between digestive symptoms and biological markers (IFABP).(at day 1)