JPRN-jRCTs031190054已完成未知
In vivo quantification of central phosphodiesterase 7 using [11C]MTP38
Tagai Kenji0 个研究点目标入组 7 人开始时间: 2019年7月12日最近更新:
试验速览
- 阶段
- 未知
- 状态
- 已完成
- 发起方
- 入组人数
- 7
研究概览
简要总结
The distribution of [11C]MTP38 is consistent with that of PDE7, and kinetic analysis using arterial blood samples showed that it could be quantified by the reference tissue method, indicating that it is a promising ligand for clinical use.Besides, the investigation in combination with MRI suggested that it is useful for voxel-based analysis and applied analysis with MRI.
研究设计
- 研究类型
- Interventional
入排标准
- 年龄范围
- >= 20age old 至 < 50age old（—）
- 性别
- Male
入选标准
- •Healthy male subjects
排除标准
- •1.Subjects who do not have ability to make informed consent.
- •2. Subjects with any psychiatric disorder or subjects with severe physical complication.
- •3. Subjects who currently smokes.
- •4. Subjects with any organic brain disorder.
- •5. Subjects with metallic medical device in the body.
- •6. Subjects with tattoo.
- •7. Subjects with severe claustrophobia.
- •8. Subjects with a history of allergy to heparin and local anesthetics.
- •9. Subjects who are taking an anticoagulant.
- •10. Subjects who has participated in other study in recent 6 months.
- •11. Subjects who has participated in blood donation in recent 12 weeks.
- •12. Subjects who is considered to be inappropriate to participate in the study.
研究者
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