Relation Between Nutrition and Frailty in Community-dwelling Older Persons
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 206
- 试验地点
- 1
- 主要终点
- Frailty (according to Fried et al.)
研究概览
简要总结
The purpose of this study is to investigate the association between nutrition and frailty in older community-living persons.
详细描述
Nutrition is regarded as an important etiologic factor in the development of frailty in older adults. To date the relation between nutrition and frailty is only poorly described.
Thus, it is the purpose of this study to investigate the association between different nutrition characteristics and frailty in older community-living persons.
206 volunteers aged 75 years or older were included in this cross-sectional study. Nutritional assessment included the Mini-Nutritional Assessment (MNA), a food-frequency questionnaire and a standardised three-day dietary record. Intake of energy and nutrients was calculated using the German nutrient database BLS II.2. Dietary patterns were described by different dietary scores. Frailty was defined according to Fried et al. based on the following criteria: weight loss, exhaustion, grip strength, walking speed and physical activity. In addition several standardised tests were performed to characterise physical performance (Timed Up & Go, repeated chair stands, balance tests).
The association between nutritional aspects and physical performance is evaluated in an explorative manner.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Cross Sectional
入排标准
- 年龄范围
- 75 Years 至 —（Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •age of 75 years and older
- •living independently at home
排除标准
- •acute illness
- •cognitive impairment (Mini Mental State Examination ≥ 24 out of 30 points)
结局指标
主要结局
Frailty (according to Fried et al.)
时间窗: 1 day
Frailty is defined as the presence of at least 3 of the following criteria: * self-reported weight loss of more than 4.5 kg in the last year * exhaustion (self-reported feeling that everything was an effort or one could not get "going" \> 2 times a week) * low grip strength (men ≤ 29-32 kg, women ≤ 17-21 kg depending on BMI), * low walking speed (\> 6-7 sec/ 4.57 m, depending on gender and height) * low physical activity (men \< 383 kcal/ week, women \< 270 kcal/ week)
次要结局
- Impaired physical performance (according to Guralnik et al.)(1 day)
研究者
Dorothee Volkert
Professor Dr.
University of Erlangen-Nürnberg Medical School