NCT04374188Unknown不适用
Efficacy of Ciprofloxacin Therapy in Avoidance of Sepsis in Patient Undergoing Percutanous Nephrolithotomy: A Randomized Controlled Trial
Diaa Eldin Taha Ramadan Mohamed1 个研究点 分布在 1 个国家目标入组 200 人开始时间: 2019年9月1日最近更新:
适应症
干预措施
相关药物
试验速览
- 阶段
- 不适用
- 发起方
- 入组人数
- 200
- 试验地点
- 1
- 主要终点
- Effect of ciprofloxacin versus levofloxacin duration before PCNL
研究概览
简要总结
Efficacy of ciprofloxacin therapy in avoidance of sepsis in patient undergoing percutanous nephrolithotomy. A randomized controlled trial.
详细描述
To figure out the value of oral ciprofloxacin medication in ameliorate the outcome of renal nephrolithiasis extraction via the endoscope as regard the sepsis.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Double (Care Provider, Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patient 18 years or older
- •Stones ≥ 2 cm and/or mild to moderate hydronephrosis
- •Sterile mid urine stream
排除标准
- •Patients with a stent, nephrostomy tube or indwelling catheter
- •Renal failure
- •Fever before surgery
- •Previous manipulation/procedure
- •Concomitant bladder stone or tumour
- •Patients with active UTI
- •Contralateral renal/ureteric stone
研究组 & 干预措施
ciprofloxacin
Active Comparator
ciprofloxacin tablets
干预措施: Ciprofloxacin (Drug)
levofloxacin
Active Comparator
levofloxacin tablets
干预措施: Levofloxacin (Drug)
结局指标
主要结局
Effect of ciprofloxacin versus levofloxacin duration before PCNL
时间窗: 12 months
To evaluate whether 7 days of ciprofloxacin or levofloxacin before PCNL, can reduce upper urinary tract infection and urosepsis after PCNL.
次要结局
- predictors of systemic inflammatory response syndeome (SIRS) and sepsis post PCNL.(12 months)
- differences between Culture and sensitivity (C&S) of Preoperative urine (MSU) and intraoperative renal pelvic urine(12 months)
研究者
Diaa Eldin Taha Ramadan Mohamed
Lecturer of urology
Kafrelsheikh University
研究点 (1)
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