Comparison of effectiveness of Ciprofloxacin and Cefpodoxime in patients with acute attack of chronic middle ear infectio
- Conditions
- Health Condition 1: H661- Chronic tubotympanic suppurative otitis mediaHealth Condition 2: null- Mild to moderate cases of acute exacerbation of chronic suppurative otitis media
- Registration Number
- CTRI/2011/10/002079
- Lead Sponsor
- Arijit Ghosh
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 42
1.Adults of either sex
2.Aged between 18 and 60
3.Clinically documented cases of tubo-tympanic type chronic suppurative otitis media defined as long standing chronic suppuration of middle ear cleft and its muco-periosteal lining resulting in discharging ear and deafness presenting with clinical symptoms and signs of acute exacerbation of the disease
4.Baseline otological symptom score of more than 4 but less than 8
1.Female patients who are pregnant or lactating 2.Severe cases of AECSOM for which hospitalization or parenteral antibiotic treatment is required and
3. Patients with otological symptom score of less than4 and more than 8 will be also excluded from the study.
4.Patients with foul smelling discharge and those who received antibiotic in preceding 4 weeks of screening will be left out.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Clinical cure <br/ ><br> <br/ ><br>Subject will be categorized as clinical cure if otological symptom score is less than 3 at the day 14 visit.Timepoint: day 14 visit
- Secondary Outcome Measures
Name Time Method Clinical improvement <br/ ><br> <br/ ><br>Subject will be categorized as clinical improvement if there is at least one scale one scale reduction from baseline score between 3 to 5 at the day 14 visit assessment.Timepoint: day 14 visit