Comparison of effect of perioperative infusion of lidocaine vs dexmedetomidine on post operative pain in patients undergoing laparoscopic cholecystectomy
试验速览
- 阶段
- 1/2 期
- 状态
- 已完成
- 发起方
- 入组人数
- 66
- 试验地点
- 1
- 主要终点
- The Efficacy of Intravenous Lidocaine or Intravenous Dexmedetomidine for post operative pain relief following laparoscopic cystectomy would be determined by this study
研究概览
简要总结
The Efficacy of Intravenous Lidocaine or Intravenous Dexmedetomidine for post operative pain relief following laparoscopic cystectomy would be determined by this study.
Dexmedetomidine offers significant advantagesover lidocaine in terms of postoperative pain control and reduced analgesicrequirements
Post-operativesedation scores and recovery profile were generally comparable between the twogroups. On the basis of these findings, it could be inferred that perioperativeinfusion of both lidocaine as well as dexmedetomidine was effective in delayingthe post-operative rescue analgesic need with almost similar recovery profile.However, of the two dexmedetomidine had a slight edge over lidocaine both interms of analgesic effect as well as recovery profile.
研究设计
- 研究类型
- Interventional
- 分配方式
- Computer generated randomization
- 盲法
- Not Applicable
入排标准
- 年龄范围
- 18.00 Year(s) 至 60.00 Year(s)（—）
- 性别
- All
入选标准
- •Patients undergoing Laparoscopic Cholecystectomy under General Anesthesia.
- •Age between 18 – 60 years ASA Grade I and II.
排除标准
- •BMI >30kg/m
- •Pregnant and Lactating mothers Patients having sinus bradycardia or heart blocks, Patients On steroids.
- •History of Allergy to study drugs.
结局指标
主要结局
The Efficacy of Intravenous Lidocaine or Intravenous Dexmedetomidine for post operative pain relief following laparoscopic cystectomy would be determined by this study
时间窗: Surgery of max 1hr15mins and followed up for 12hours postoperative period.
次要结局
- The Efficacy of Intravenous Lidocaine or Intravenous Dexmedetomidine for Recovery profile & time to first rescue analgesic following laparoscopic cystectomy would be determined by this study(Surgery of max 1hr15mins & followed up for 12hours postoperative period)