Safety and Feasibility of Atropine Added During Treadmill Stress Testing in Patients With Chronotropic Incompetence or Poor Exercise Capacity.
试验速览
- 阶段
- 3 期
- 状态
- 已完成
- 入组人数
- 103
- 试验地点
- 1
- 主要终点
- 1- To characterize patients who can't achieve target heart rate at treadmill exercise test.2- To evaluate atropine added during treadmill stress testing in order to increase heart rate and achieave conclusive test.
研究概览
简要总结
The aim of this study is to evaluate the Safety and feasibility of atropine added during treadmill stress testing in patients with chronotropic incompetence or poor exercise capacity.
Our hypothesis is that we can increase heart rate by using atropin in these patients, so we will achieve more conclusive results.
研究设计
- 研究类型
- Interventional
- 分配方式
- Non Randomized
- 干预模型
- Single Group
- 主要目的
- Diagnostic
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- Female
- 接受健康志愿者
- 否
入选标准
- •Patients with chest pain without evidence of ischemia eligible for exercise test.
- •Age> 18 years old
排除标准
- •Patients with LBBB
- •Unstable Angina
- •Recent Myocardial Infarction
- •Un controlled Arrythmia
- •Congestive heart faliure
- •Severe symptomatic valvular heart disease
- •Acute Pulmonary Embolism
- •Acute perimyocarditis
- •Acute aortic dissection
- •Lt main stenosis
- •Severe hypertention (Systolic> 200 mmHg; Diastolic > 100 mmHg)
- •Cardiomyopathy
- •Obstructiove abnormalities
- •Psychiatric disorders
- •High degree AV Block
研究组 & 干预措施
1
Pateints who achieve target haert rate or conclusive test will not be given Atropine
干预措施: Atropine (Drug)
2
Patients who won't achieve tarhet heart rate or conclusive results will be given Atropine
干预措施: Atropine (Drug)
结局指标
主要结局
1- To characterize patients who can't achieve target heart rate at treadmill exercise test.2- To evaluate atropine added during treadmill stress testing in order to increase heart rate and achieave conclusive test.
时间窗: 1 yaer
次要结局
未报告次要终点
研究者
Mohamed Jabaren
MD
HaEmek Medical Center, Israel