EUCTR2005-004012-78-AT进行中（未招募）1 期
Effects of acarbose on endothelial function, platelet activity, insulin sensitivity and glucose control in subjects with coronary artery disease and new onset type-II diabetes.
Medical University of Graz0 个研究点目标入组 56 人开始时间: 2005年11月11日最近更新:
相关药物
试验速览
- 阶段
- 1 期
- 状态
- 进行中（未招募）
- 发起方
- 入组人数
- 56
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional clinical trial of medicinal product
入排标准
- 性别
- All
入选标准
- •Age 40-70 years
- •Angiographically verified coronary artery disease (> 50 % stenosis)
- •Diabetic oGTT at the occasion of angiography
- •Are the trial subjects under 18? no
- •Number of subjects for this age range:
- •F.1.2 Adults (18-64 years) yes
- •F.1.2.1 Number of subjects for this age range
- •F.1.3 Elderly (>=65 years) yes
- •F.1.3.1 Number of subjects for this age range
排除标准
- •Acute coronary syndrome or cerebrovascular event within the previous 8 weeks
- •Acetylsalicylic acid at a dose > 100 mg daily
- •Any other NSAID or antiplatelet drug
- •BMI > 35 kg/m2
- •HbA1c > 7.5 %
- •Serum creatinine > 2.5 mg/dl
- •GOT/GPT > 3x upper limit of normal
- •Heart failure > class NYHA II
- •Uncontrolled hypertension (blood pressure > 165 / 100 mmHg)
- •New onset statin or ACE-inhibitor within the previous 8 weeks
- •Known intolerance of acarbose
- •Chronic inflammatory bowel disease
- •Malabsorption syndromes
- •any antidiabetic medication
研究者
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