Role of Salbutamol in the Management of Transient Tachypnea of the New Born
试验速览
- 阶段
- 1 期
- 状态
- 已完成
- 入组人数
- 60
- 试验地点
- 1
- 主要终点
- Salbutamol nebulization improved transient tachypnea of the new born compared to normal saline nebulization alone.
研究概览
简要总结
Role of Salbutamol in the management of transient tachypnea of the new born
详细描述
Role of Salbutamol in the management of transient tachypnea of the new born Abstract:
Background Transient tachypnea of the newborn (TTN) is a common respiratory disorder in the early neonatal period due to delayed clearance of fetal lung fluid. Salbutamol, a β2-adrenergic agonist, may enhance lung fluid clearance through stimulation of epithelial sodium channels and Na-K-ATPase. However, the therapeutic role of Salbutamol in TTN management remains controversial with limited clinical evidence, necessitating further investigation.
Objective:
To compare the mean change in transient tachypnea of newborn score with inhaled salbutamol and normal saline.
Study Design:
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 1 Day 至 28 Days（Child）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Neonates with transient tachypnea
排除标准
- •age above 28 days
- •Other diseases than transient tachypnea of the new born
研究组 & 干预措施
Role of Salbutamol in the management of transient tachypnea of the new born
Salbutamol treatment compared to normal saline in patients with transient tachypnea of the new born
干预措施: Salbutamol (Ventolin®) (Drug)
结局指标
主要结局
Salbutamol nebulization improved transient tachypnea of the new born compared to normal saline nebulization alone.
时间窗: 4 months
Two study groups ,one using Salbutamol nebulization and other using normal saline nebulization . The one group with Salbutamol nebulization improved a lot than the group using normal saline nebulization. The study was conducted in Khyber Teaching Hospital Peshawar neonatal unit .
次要结局
未报告次要终点
研究者
Hayat Ullah
Doctor, pediatrics specialist
Khyber Teaching Hospital