Project PROTECT: Protecting Nursing Homes From Infections and Hospitalization
试验速览
- 阶段
- 4 期
- 状态
- 已完成
- 入组人数
- 13,952
- 试验地点
- 28
- 主要终点
- Hospital Transfers Due to Infection
研究概览
简要总结
This is a cluster-randomized trial of nursing homes to assess whether decolonization with routine chlorhexidine bathing and periodic use of nasal antiseptics can reduce hospitalizations associated with infections, antibiotic utilization, and multi-drug resistant organism (MDRO) prevalence. The comparator arm will be routine bathing care.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Prevention
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- 未提供
排除标准
- 未提供
研究组 & 干预措施
Decolonization
Nursing homes assigned to this arm will perform decolonization using topical antiseptic products.
干预措施: Chlorhexidine gluconate (CHG) (Drug)
Decolonization
Nursing homes assigned to this arm will perform decolonization using topical antiseptic products.
干预措施: Iodophor (10% povidone-iodine) (Drug)
结局指标
主要结局
Hospital Transfers Due to Infection
时间窗: 18 months
Probability that a transfer to a hospital is due to an infection
次要结局
- All Hospital Transfers(18 months)
研究者
Susan Huang
Professor and Medical Director of Epidemiology and Infection Prevention
University of California, Irvine