NCT04244409Unknown不适用
INvestigational Study Into Transplantation of the Uterus
适应症
试验速览
- 阶段
- 不适用
- 入组人数
- 10
- 试验地点
- 1
- 主要终点
- Live birth rate
研究概览
简要总结
Observational study on cohort of 10 women undergoing uterine transplantation using deceased donors
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 24 Years 至 38 Years（Adult）
- 性别
- Female
- 接受健康志愿者
- 否
入选标准
- •Age - 24-38 (or 40 if eggs frozen <38)
- •Normal length vagina
- •No renal pathology
- •BMI <30kg/m2
- •ASA grade I
- •Meet psychological criteria
- •Meet HFEA criteria for IVF
- •Eligible for NHS treatment
- •Speak fluent English
排除标准
- •Unsuccessful oocyte retrieval (<10 good quality embryos)
- •Previous multiple/significant surgeries
- •Severe endometriosis
- •Cancer patients <5 years in remission
- •Previous living childbirth, adopted child or child born through surrogacy
- •HIV or Hepatitis B / C positive
- •Skin or intestinal neovagina
结局指标
主要结局
Live birth rate
时间窗: 5 years
次要结局
- Pregnancy rate(5 years)
- Transplant success rate(3 years)
研究者
Ben Jones
Principal Investigator
Imperial College Healthcare NHS Trust
研究点 (1)
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