The Evaluation of the Effects of Intravenous Fluids on Perfusion Index and Pleth Variability Index
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 93
- 试验地点
- 1
- 主要终点
- Perfusion index
研究概览
简要总结
This study is aimed to assess the effects of intravenously administered three fluid types on perfusion index and pulse variability index in patients during preoperative period. Patients will be randomly divided into three groups. Baseline, 5th, 10th, 15th, 20th, 25th and 30th min non-invasive blood pressure, oxygen saturation, heart rate, room temperature, perfusion index and pulse variability index will be measured and recorded.
详细描述
Intravenous volume replacement alter the dynamics of microcirculation. Perfusion index and pulse variability index are the recent parameters to evaluate the tissue microcirculatory condition. This study is aimed to assess the effects of intravenously administered three fluid types on perfusion index and pulse variability index in patients during preoperative period. Patients will be taken to recovery room in the operating theatre and wait for 15 minutes to balance the skin temperature of the patients to the environment. Patients will be randomly divided into three groups using closed envelope technique as Group L (received 500 ml of Ringer's lactate), Group S (500 ml of saline) and Group H (received 500 ml of 6% hydroxyethylstarch). Baseline, 5th, 10th, 15th, 20th, 25th and 30th min non-invasive blood pressure, oxygen saturation, heart rate, room temperature, perfusion index and pulse variability index will be measured and recorded.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Basic Science
- 盲法
- Single (Participant)
入排标准
- 年龄范围
- 18 Years 至 45 Years(Adult)
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •having a fasting period of 8 hours
- •quit smoking for 8 hours before the procedure
排除标准
- •not to participate in the study
- •presence of peripheral vascular disease
- •a history of upper extremity surgery
- •presence of any kind of psychiatric disease
研究组 & 干预措施
sodium chloride
0.9% isotonic sodium chloride, 500 ml, one package in 30 minutes
干预措施: sodium chloride (Drug)
Hydroxyethylstarch
6% hydroxyethylstarch, 500 ml, one package in 30 minutes
干预措施: Hydroxyethylstarch (Drug)
Ringer-Lactate Infusion Solution Bag
Ringer's lactate, 500 ml, one package in 30 minutes
干预措施: Ringer-Lactate Infusion Solution Bag (Drug)
结局指标
主要结局
Perfusion index
时间窗: six months
The perfusion of the tissues
次要结局
- Pulse variability index(six months)
- Blood pressure(six months)
- Heart rate(six months)
- Oxygen saturation(six months)
研究者
Serkan Dogru
Assistant Professor
Tokat Gaziosmanpasa University
