A RANDOMIZED CONTROLLED TRIAL TO EVALUATE THE ADD-ON EFFECT OF AYURVEDIC MODULE ON ANTI-INFLAMMATORY CYTOKINE IL-10 IN NIGHT SHIFT WORKERS

Night shift work induces sleep deprivationwhich, in turn, alters the daily levels of alertness and job performance, favoringfatigue. Moreover, fatigue reduces performance and job satisfaction, favoringabsence due to sickness, absenteeism, turnover, and job attrition and ofteninduces use of psychotropic drugs. In a study by Jamal and Baba, rotating shiftnurses showed a lower degree of job satisfaction. Decreased job satisfaction isstrongly associated with increased job stress. According to past studies, pro-inflammatorycytokines were found to be elevated in highly stressed individuals. However,inflammation is body’s defense mechanism in response to illnesses, caused dueto pathogens. Therefore, interventions that aim to reducesystemic inflammation may not only help in the management of chronic disorders,but also in the prevention of these disorders in individuals having anincreased risk. In a past study it was proven that yogapractices could increase anti-inflammatory cytokine in industrial workers.Particularly, industrial workers, who are in direct contact with thepollutants, are affected most due to ill effects of pollutants. Exposure tothese pollutants leads to a systemic inflammatory response which can bemeasured in terms of pro-inflammatory and anti-inflammatory markers. So, the measures are necessity of the hour thatcan increase the anti-inflammatory cytokines and decrease the pro-inflammatorycytokines. So in this present study we will access add on effect of Ayurvedamodule on one of these marker namely anti-inflammatory cytokine IL-10.