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临床试验/NCT04585802
NCT04585802已完成不适用

Expansion and Reevaluation of the Implicit Association Test in Suicide Ideators and Suicide Attempters

University of Bern1 个研究点 分布在 1 个国家目标入组 447 人开始时间: 2020年5月27日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
447
试验地点
1
主要终点
Implicit Association Test (IAT)

研究概览

简要总结

A new approach to investigate suicidal processes belongs to the broader neurocognitive picture and are so-called implicit associations. In dual process models of information processing a second functioning mode, the automatic processing mode, complements the conscious processing. Suicidal persons tend to have a stronger implicit association with "death" than non-suicidal persons. In this study, implicit associations between different unconscious cognitive constructs are compared among suicidal and non-suicidal patients. Therefore, an adapted version of the computer-based reaction time task (IAT-S) will be used.

Four different versions of IATs are tested in this study. In the first version the implicit association between "self / others" and "death / life" is assessed (1). The second and third version measures the emotional evaluation of "death" (2) and "life" (3). In addition, in the fourth version the implicit association between death / life and internal / external locus of control is assessed (4).

The implicit associations of these four IAT-S versions are compared between three groups: patients with suicidal behavior, patients with suicidal ideation, and a clinical group without previous suicide attempts and without suicidal ideation.

The following hypotheses are made: in all four versions of the IAT-S, patients with previous suicidal behavior will have stronger implicit associations: between "self" and "death" as well as "death" and "internal locus of control" compared to all other groups. With a more "positive" evaluation of "death" and a more "negative" evaluation of "life" than all other participants.

详细描述

In this study, four versions of the suicide-specific implicit association tests (IAT-S) are carried out. Previous studies have shown that suicidal persons have stronger associations between the constructs "self" and "death". Furthermore, the strength of these implicit associations increases the risk of suicidal behavior in the follow-up period of six months by a factor of six. In these previous studies, the implicit "self-death association" (the so-called death-identity bias) was investigated. This study will additionally examine an implicit emotional evaluation (death-evaluation-bias). Therefore, two new versions of the IAT-S, which measure how death vs. life are emotionally evaluated, are being tested. In addition, a fourth version of the IAT-S was added and aims to clarify the implicit association between death / life and internal / external locus of control. Previous studies have shown that an internal locus of control is a protective factor and an external locus of control a risk factor for suicide attempts. In the present study, these four IAT-S versions are carried out with different groups of patients: patients with a suicide attempt (1), patients with suicide ideation (2) and patients with neither a suicide attempt nor suicide ideation (3). This cross sectional design allows us to test for group differences in regard to unconscious implicit associations. Hypothesis are described separately for each version of the IAT-S.

Death association: patients in group 1 will have a higher implicit association between self and death than patients in group 2 and that patients in group 2 have a significantly higher implicit association between self and death than patients in group 3.

Death evaluation: patients in group 1 will have more "positive" evaluations of "death" than patients in group 2 and patients in group 2 have a more "positive" evaluations of death than patients in group 3.

Locus of control: patients in group 1 will have a stronger association between internal locus of control and death (a) and external locus of control and life (b) than patients in group 2, and that patients in group 2 have a significantly stronger association between internal locus of control and death (a) and external locus of control and life (b) than patients in group 3.

研究设计

研究类型
Observational
观察模型
Case Control
时间视角
Cross Sectional

入排标准

年龄范围
18 Years 至 65 Years(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • Age 18-65 years
  • Ability and willingness to participate in the study
  • Ability to give consent

排除标准

  • Foreign language
  • Diagnostic criteria: Psychoses, strong cognitive impairments (e.g. dementia)

结局指标

主要结局

Implicit Association Test (IAT)

时间窗: One assessment at baseline after study information and informed consent was given

The German version of the Suicide Implicit Association Test (Rath et al., 2018) is administered using a computer paradigm and is designed to measure implicit associations with death using D-values. D is an individual effect size assessment that reflects the comparative difficulty of performing the two response conditions of the IAT, with a value of 0 indicating that the tasks had equivalent performance (Greenwald et al., 2003). D has a theoretical minimum of -2 and maximum of +2 when blocks of the same size are compared (Nosek \& Sriram, 2007). The more positive the D-values, the stronger the association between the "self" and "death" than between the "self" and "life".

次要结局

  • Internal External Locus of Control-4 (IE-4)(One assessment at baseline after study information and informed consent was given)
  • Positive Mental Health Scale (PMH-scale)(One assessment at baseline after study information and informed consent was given)
  • Suicide Behaviors Questionnaire - Revised(One assessment at baseline after study information and informed consent was given)
  • Beck Scale for Suicide Ideation (BSS)(One assessment at baseline after study information and informed consent was given)
  • Beck Depression Inventory (BDI-II)(One assessment at baseline after study information and informed consent was given)
  • Mee-Bunney Psychological Pain Assessment Scale (MBPPAS)(One assessment at baseline after study information and informed consent was given)
  • Mini-International Neuropsychiatric Interview (M.I.N.I.)(One assessment at baseline after study information and informed consent was given)

研究者

申办方类型
Other
责任方
Sponsor

研究点 (1)

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