Post-Extraction Wound Healing in Elderly
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 入组人数
- 72
- 试验地点
- 1
- 主要终点
- IL1B
研究概览
简要总结
Patients presenting to the University of Nebraska Medical Center College of Dentistry for a posterior extraction will be offered participation in the study. Prior to extraction, subjects will undergo clinical measurements, xray, gingival crevicular fluid (GCF) and saliva sampling and a blood draw. Following atraumatic tooth extraction, the subjects will be reevaluated for healing at 1, 2-weeks and 3 months. At each appointment, GCF, saliva and wound fluid (WF) will be collected and at 3 months a second xray will be taken.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 65 Years 至 80 Years（Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •needs posterior tooth extracted
- •no systemic conditions or meds affecting wound healing
- •non-smoker
排除标准
- •systemic conditions or meds known to affect wound healing
结局指标
主要结局
IL1B
时间窗: Baseline
Measurement of IL1B in GCF, WF
Interleukin-1 beta (IL1-B)
时间窗: Baseline
Measurement of IL1B in GCF, WF
Amount of Interleukin-1 beta (IL1-B) in gingival crevicular at baseline
时间窗: Baseline
Measurement of IL1B in GCF
次要结局
- Bone Density(3 months)