Non-invasive Brain Stimulation to Enhance the Effects of Training in Healthy Old and Patients With Focal Brain Lesions
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 88
- 试验地点
- 2
- 主要终点
- Motor performance
研究概览
简要总结
The goal of this study is to investigate the impact of non-invasive brain stimulation on motor skill acquisition in healthy individuals. Participants performed a motor task with non-invasive brain stimulation applied over the area of the brain where movements were controlled. The study compared motor skill performance between with the active stimulation and the placebo stimulation.
详细描述
This study implemented a randomized, double-blinded, and sham-controlled design, investigating the effects of non-invasive brain stimulation on motor skill acquisition in healthy individuals.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Basic Science
- 盲法
- Double (Participant, Investigator)
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •age equals to or over 18 years old
- •absence of major neurological, psychiatric and physical impairment, with normal or corrected to normal vision
- •right handed
- •in good general health
排除标准
- •professional musicians/stenotypist
- •unable to consent
- •unable to perform the task as required (instructions and setup)
- •exclusion criteria for magnetic resonance imaging (MRI), transcranial electrical stimulation (tES), transcranial magnetic stimulation (TMS)
研究组 & 干预措施
Verum
anodal transcranial direct current stimulation
干预措施: Verum (Other)
Placebo
40 seconds of stimulation delivered at the beginning of training (with 8 seconds ramp-up and 5 seconds ramp-down times)
干预措施: Placebo (Other)
结局指标
主要结局
Motor performance
时间窗: From the start of the practice to the end of training at 5 days (and follow up on the 10th day and 60th day)
Replication of a nine-digit sequence displayed on a screen, as quickly and as accurately as possible, using the left hand
Motor performance
时间窗: From the start of the practice to the end of training at 5 days (and follow up on the 10th day and 60th day)
Replication of a nine-digit sequence displayed on a screen, as quickly and as accurately as possible, using the left hand
次要结局
未报告次要终点
研究者
Friedhelm Hummel
Full professor
Ecole Polytechnique Fédérale de Lausanne