Nutritional Management of Sarcopenia in Patients With Heart Failure
试验速览
- 阶段
- 不适用
- 状态
- 进行中(未招募)
- 发起方
- 入组人数
- 60
- 试验地点
- 2
- 主要终点
- Muscle mass
研究概览
简要总结
Sarcopenia is a frequent complication in patients with cancer and chronic diseases, it is characterized by decreased muscle strength and fatigue due to reduced skeletal muscle mass, which is accompanied by atrophy and decreased quality of muscle tissue. In all cases, it negatively impacts treatment tolerance, clinical outcomes and survival, in consequence, quality of life of these patients decreases while morbidity, mortality and costs increase. In this context, appropriate nutritional screening and early nutrition support are extremely recommended, to this aim, in some cases, oral nutritional supplements (ONS) are necessary; ONS could have a standard formula or be enriched with specific nutrients. There is a lack of evidence for supporting its use or the use of protein modules in other clinical conditions including patients with heart failure
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 —(Adult, Older Adult)
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients with a previous admission due to HF in the previous 12 months
- •Moderate or severe LVEF
- •Both sexs
- •Age >18 years old.
排除标准
- •MDRD <15 ml/min
- •End-stage liver disease.
结局指标
主要结局
Muscle mass
时间窗: 6 months
Changes in muscle mass
Functionality
时间窗: 6 months
Changes in functionality determined by the up and go test
次要结局
- Albumin(6 months)
- C-RP(6 months)
