Analysis of Protein Expression in Serum of Subjects With Knee Arthritis Control Group and Evaluation by Meridian and Pulse Wave Energy
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 50
- 试验地点
- 1
- 主要终点
- Micro-Western Array and Enzyme-linked immunosorbent assay
研究概览
简要总结
In the previous study "Using omics technology to explore the mechanism of acupuncture treatment of different acupoints of knee osteoarthritis: a randomized controlled trial (CMUH109-REC3-113)", we found that acupuncture for knee osteoarthritis(KOA) significantly reduces inflammation, apoptosis, and metabolism-related serum protein profiles. However, due to the lack of serum protein data from the control group, it is impossible to establish standard values for comparison. To analyze the protein expression in the serum of KOA control group subjects, we also measured the spectral energy values of the radial artery pulse wave obtained from the pulse sphygmograph and the meridian energy values obtained from Ryodoraku. The results obtained can be compared with previous studies, thus this experiment was designed.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Basic Science
- 盲法
- None
入排标准
- 年龄范围
- 50 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Adults over 50 years old without knee pain
排除标准
- •Clinical diagnosis of knee osteoarthritis
- •Taking anti-inflammatory and analgesic drugs in the past month
- •Taking blood-lipid-lowering drugs or health foods in the past month
- •Received any acupuncture treatment in the past 3 weeks
结局指标
主要结局
Micro-Western Array and Enzyme-linked immunosorbent assay
时间窗: the first and the fifth weeks
Obtaining the serum protein content value
次要结局
- pulse sphygmograph and Ryodoraku(the first and the fifth weeks)